Comparing different materials for dental restorations

Comparative Evaluation of Class V Restorations: 2-Year Randomized Double-Blind Trial Comparing Ion-Releasing Materials and Resin Composite

Not applicable Interventional Mansoura University · NCT06164418

This study is testing how well different materials for dental fillings work over two years in adults to see which ones last longer and perform better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages35 Years to 50 Years
SexAll
SponsorMansoura University Academic / other
Locations1 site (Mansoura, Dakahliya)
Trial IDNCT06164418 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the two-year performance of Class V dental restorations using various restorative systems, including both ion-releasing and non-ion-releasing composites. It employs a double-blinded randomized design to ensure unbiased results, with 100 adult patients participating from the Operative Department clinic at the Faculty of Dentistry, University of Mansoura. Participants will receive informed consent and will be monitored for restoration success over the study period from November 2023 to November 2025.

Who should consider this trial

Good fit: Ideal candidates are adults with a primary cervical caries on the buccal surface of their posterior teeth and good oral hygiene.

Not a fit: Patients with high caries risk, poor oral hygiene, or those undergoing orthodontic treatment may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved dental restoration techniques, enhancing patient outcomes and reducing the incidence of restoration failure.

How similar studies have performed: Previous studies on dental restorations with ion-releasing materials have shown promising success rates, indicating that this approach has been tested with favorable outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with one primary cervical caries on the buccal surface of any of their upper or lower posterior teeth. The cervical lesions must have an enamel margin occlusally and a cervical dentin margin
* Patients must have a good oral hygiene;
* Patients with tooth gives a positive response to testing with an electric pulp tester
* Patients with normal and full occlusion,
* Patients with opposing teeth should be natural with no restorations.

Exclusion Criteria:

- High caries risk patients with extremely poor oral hygiene,

* Patients involved in orthodontic treatment or periodontal surgery,
* Patients with periodontally involved teeth (chronic periodontitis)
* Patients with heavy bruxism habits and clenching

Where this trial is running

Mansoura, Dakahliya

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Secondary CariesDental Restoration Failure of Marginal Integrity
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.