Comparing different graft materials for dental implant soft tissue thickness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the changes in soft tissue volume around dental implants using three different graft materials: sub-epithelial connective tissue grafts from the palate, porcine collagen matrix, and porcine acellular dermal matrix. Participants will receive a single dental implant and undergo soft tissue augmentation to address issues like buccal defects and thin biotype. The effectiveness of each graft material will be assessed at 3 and 15 months post-implant placement, focusing on volume gain and stability. Patient-reported outcomes will also be measured to evaluate overall satisfaction and aesthetic results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients referred to Department of Periodontology (CUO) in need of a single implant and need of soft tissue augmentation such as buccal defects, thin biotype, lack of keratinized tissue and aesthetic compromised situation.

* The patient must be ≥18 years and able to understand the nature of the proposed surgery and must sign an informed consent.
* The implant must be located between 2 fixed reference points (i.e. clinical crowns).
* Anterior and premolar teeth (from premolar to premolar).
* Enough crestal bone width to leave a minimum thickness of 2mm at the buccal bone plate when placing the implant.
* Palate must have ≥2mm of thickness at premolar area.
* Full mouth plaque and bleeding score \<20%.

Exclusion Criteria:

* Pregnant or lactation.
* Active periodontal disease.
* Previous soft tissue augmentation in the area.
* Need of guided bone regeneration (GBR) during or after the placement of the implant.
* Heavy smokers (\> 10 cigarettes per day).
* Local or systemic conditions that would interfere with routine periodontal therapy (non-controlled diabetes mellitus, cancer, HIV, Chronic High dose steroid therapy, bone metabolic diseases, radiation, immunosuppressive disorders, liver function disorder, immunosuppressant disease, autoimmune disease).
* Allergy to non-steroidal anti-inflammatory drugs.
* Patients taking medications that cause gingival enlargement.

Where it's running

• Universitat Internacional de Catalunya
  Sant Cugat del Vallès, Barcelona, Spain Recruiting

Study contacts

• Principal investigator: Andres Pascual La Rocca, DDS — Universitat Internacional de Catalunya
• Study coordinator: Andres Pascual La Rocca, DDS
• Email: pascuallarocca@hotmail.com
• Phone: 0034627725044

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.