Comparing different feeding methods for critically ill patients with gastrointestinal dysfunction
Effect of Different Feeding Method on Gastrointestinal Function of Critical Patients
This study tests different ways of feeding critically ill patients with gut problems to see which method helps them recover better and stay in the ICU for a shorter time.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Sex | All |
| Sponsor | Guangdong Provincial Hospital of Traditional Chinese Medicine Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT04224883 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of various enteral feeding methods on gastrointestinal function in septic patients. It compares continuously pumped feeding over 24 hours, continuously pumped feeding over 16 hours, and intermittent feeding through a stomach tube. The goal is to determine which method best improves intestinal motility and mucosal barrier function, potentially reducing ICU mortality and length of stay. The study focuses on patients with a high APACHE-II score, indicating severe illness.
Who should consider this trial
Good fit: Ideal candidates are septic patients in critical care with an APACHE-II score greater than 15.
Not a fit: Patients who are fasting due to gastrointestinal perforation, bleeding, or postoperative conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved gastrointestinal function and outcomes for critically ill patients, potentially reducing mortality and ICU stay duration.
How similar studies have performed: While early enteral nutrition has shown benefits in septic patients, the specific comparison of different feeding methods is less explored, making this approach somewhat novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Septic patients in Department of Critical Care Medicine, Guangdong Provincial Hospital of Chinese Medicine; 2. APACHE-Ⅱ score greater than 15 points; 3. Signing the informed consent. Exclusion Criteria: 1. Fasting patients in the clinical, such as digestive tract perforation, bleeding or postoperative patients with gastrointestinal tract; 2. Allergic to enteral nutrition preparations; 3. Don't want to attend the test or not with the healer.
Where this trial is running
Guangzhou, Guangdong
- 2nd Affiliated Hospital of Guangzhou University of Chinese Medicine — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Guang Yang
- Email: yangguang@gzucm.edu.cn
- Phone: 86-20-39318526
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.