Clinical trial Recruiting at 1 site Interventional Ages 50 to 75

Comparing different exercises for improving cognitive function in people with mild cognitive impairment

Official title: Comparison of the Effects of Bimanual, Finger and Virtual Reality Exercises in Individuals With Mild Cognitive Impairment - Randomized Controlled Study

Run by Eastern Mediterranean University · NCT06935812 · Data updated 2026-11-12

This study tests which type of exercise—bimanual, finger, or virtual reality—can best improve thinking skills in people aged 50-75 with mild cognitive impairment.

Quick facts

Study typeInterventional
Ages50 Years to 75 Years
SexAll
Enrollment106 (estimated)
SponsorEastern Mediterranean University
Academic / other
Locations1 site (Famagusta, Eyalet/Yerleşke)
StatusRecruiting
StartedApril 29, 2025
Main results expectedSeptember 24, 2026
Study endsSeptember 24, 2026
Registry record updatedMay 19, 2026
Trial IDNCT06935812 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 50-75 who have been diagnosed with mild cognitive impairment and can walk independently.

Probably not a fit

Patients with significant musculoskeletal disorders or neurological diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of three different types of exercises—bimanual, finger, and virtual reality exercises—on cognitive functions in individuals with mild cognitive impairment (MCI). The research aims to determine which exercise method is most effective in enhancing processing speed and overall cognitive performance. Participants aged 50-75 diagnosed with MCI will engage in these exercises, and their cognitive abilities will be assessed using standardized tests. The study seeks to provide insights into non-pharmacological interventions that could help manage MCI.

Why it matters

Potential benefit: If successful, this study could lead to improved cognitive function and quality of life for patients with mild cognitive impairment.

How similar studies have gone: Previous studies have shown promising results with similar exercise interventions for cognitive enhancement, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants who are between 50-75 years of age
* Individuals diagnosed with MCI by a geriatrician according to DSM-5 criteria,
* Who has the Montreal Cognitive Assessment score between 13-26,
* Who has the Quick Mild Cognitive Impairment screen score between 48-67,
* Who has Instrumental Activities of Daily Living Scale score ≥6/8,
* Who says yes to "Do you have a memory problem?" question,
* Who can walk independently without using any walking aids

Exclusion Criteria:

* Participants who have any musculoskeletal disorders that may cause balance and gait disorders,
* Who have central or peripheral neurological diseases (eg. stroke, Parkinson's disease or polyneuropathies),
* Who are using psychiatric drugs that may affect psychiatric disease and/or cognitive performance (Using nonsteroidal anti-inflammatory drugs more than three times a week, which may affect cognitive functions, using gingko biloba and antioxidant supplements (for example, coenzyme Q10 and alpha-lipoic acid)),
* Who has daltonism and
* Who attends any exercise program last 6 months will not be included in this study.

Where it's running

  • Eastern Mediterranean University
    Famagusta, Eyalet/Yerleşke, Cyprus
    Recruiting

Study contacts

  • Principal investigator: Betül Fatma Bilgin, MSc PT — Eastern Mediterranean University
  • Study coordinator: Betül Fatma Bilgin, MSc PT
  • Email: betulll_96@hotmail.com
  • Phone: 3926303011

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.