Comparing different exercises for improving cognitive function in people with mild cognitive impairment

Comparison of the Effects of Bimanual, Finger and Virtual Reality Exercises in Individuals With Mild Cognitive Impairment - Randomized Controlled Study

NA · Eastern Mediterranean University · NCT06935812

This study tests which type of exercise—bimanual, finger, or virtual reality—can best improve thinking skills in people aged 50-75 with mild cognitive impairment.

Quick facts

PhaseNA
Study typeInterventional
Enrollment106 (estimated)
Ages50 Years to 75 Years
SexAll
SponsorEastern Mediterranean University (other)
Locations1 site (Famagusta, Eyalet/Yerleşke)
Trial IDNCT06935812 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of three different types of exercises—bimanual, finger, and virtual reality exercises—on cognitive functions in individuals with mild cognitive impairment (MCI). The research aims to determine which exercise method is most effective in enhancing processing speed and overall cognitive performance. Participants aged 50-75 diagnosed with MCI will engage in these exercises, and their cognitive abilities will be assessed using standardized tests. The study seeks to provide insights into non-pharmacological interventions that could help manage MCI.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 50-75 who have been diagnosed with mild cognitive impairment and can walk independently.

Not a fit: Patients with significant musculoskeletal disorders or neurological diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved cognitive function and quality of life for patients with mild cognitive impairment.

How similar studies have performed: Previous studies have shown promising results with similar exercise interventions for cognitive enhancement, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants who are between 50-75 years of age
* Individuals diagnosed with MCI by a geriatrician according to DSM-5 criteria,
* Who has the Montreal Cognitive Assessment score between 13-26,
* Who has the Quick Mild Cognitive Impairment screen score between 48-67,
* Who has Instrumental Activities of Daily Living Scale score ≥6/8,
* Who says yes to "Do you have a memory problem?" question,
* Who can walk independently without using any walking aids

Exclusion Criteria:

* Participants who have any musculoskeletal disorders that may cause balance and gait disorders,
* Who have central or peripheral neurological diseases (eg. stroke, Parkinson's disease or polyneuropathies),
* Who are using psychiatric drugs that may affect psychiatric disease and/or cognitive performance (Using nonsteroidal anti-inflammatory drugs more than three times a week, which may affect cognitive functions, using gingko biloba and antioxidant supplements (for example, coenzyme Q10 and alpha-lipoic acid)),
* Who has daltonism and
* Who attends any exercise program last 6 months will not be included in this study.

Where this trial is running

Famagusta, Eyalet/Yerleşke

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Mild Cognitive Impairment, Finger Exercise, Bimanual Exercise, Virtual Reality, Processing Speed, Cognitive Functions, Walking Speed, Gross Motor Skills

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.