Comparing different combinations of medications for pain relief in hand surgery

A Comparative Factorial Study Design of Adjuvant Enhanced Ultrasound-Guided Wrist Block Anaesthesia for Hand Surgery : Bupivacane, Dexamethasone, Dexametmiodine

Phase 4 Interventional Aswan University · NCT06826690

This study is testing different combinations of pain relief medications during hand surgery to see which one helps patients feel better and for longer after the procedure.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment160 (estimated)
Ages18 Years and up
SexAll
SponsorAswan University Academic / other
Locations1 site (Aswān, Aswan Governorate)
Trial IDNCT06826690 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of ultrasound-guided wrist blocks using bupivacaine alone versus combinations of bupivacaine with dexamethasone and dexamethasone with dexametmiodine for pain management in hand surgeries. Patients aged 18 and older will be monitored for pain relief duration and satisfaction post-operatively. The study will collect baseline data such as heart rate, blood pressure, and oxygen saturation, and will assess pain levels using a numerical rating scale at specified intervals. If pain levels exceed a certain threshold, additional medication will be administered.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with an ASA classification of 1-3 who require hand surgery.

Not a fit: Patients with allergies to the medications used, pre-existing neuropathy, coagulopathy, cognitive impairment, or those who refuse to participate may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance pain management strategies for patients undergoing hand surgery.

How similar studies have performed: Previous studies have shown promising results with similar approaches in pain management, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Patients more than or equal 18 years old and are ASA 1-3

Exclusion Criteria:

* allergy to used medication
* pre exist neuropathy
* coagulapthy
* cognitive impairment
* refusal to participate
* Failed block and requiring general anesthesia

Where this trial is running

Aswān, Aswan Governorate

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hand Surgeries
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.