Comparing diabetes complications in patients with and without buffalo hump
To Compare People With T2DM Who Have Double Dorsal Cervical Fat (Double Hump) Versus Who do Not Have Double Dorsal Cervical Fat (Double Hump)
This study looks at whether having a buffalo hump affects the severity of complications in Asian Indian patients with Type 2 diabetes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 20 Years to 70 Years |
| Sex | All |
| Sponsor | Diabetes Foundation, India Academic / other |
| Locations | 1 site (New Delhi, Delhi) |
| Trial ID | NCT06386952 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the correlation between the presence of a buffalo hump and the severity of complications in patients with Type 2 Diabetes Mellitus (T2DM). Participants will be recruited from an endocrine outpatient department and will undergo a thorough clinical examination, including assessments of microvascular and macrovascular complications. The study focuses on Asian Indian patients, who are known to develop T2DM at a younger age and experience more severe complications. By comparing those with a double hump to those without, the study seeks to enhance understanding of the relationship between physical characteristics and diabetes-related health outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 20 to 70 years with a diagnosis of T2DM for up to 30 years and a BMI between 25 and 40 kg/m².
Not a fit: Patients with a BMI over 40 kg/m², severe end organ damage, or other significant chronic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved risk stratification and management strategies for patients with T2DM based on physical characteristics.
How similar studies have performed: While the specific correlation between buffalo hump and diabetes complications has not been extensively studied, similar observational studies have shown that physical characteristics can be indicative of health outcomes in diabetes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with T2DM (up to 30 years Duration) 2. Age 20 to 70 years 3. BMI \>25 kg/m² to \>40 kg/m² 4. Gender- Both (Male \& Female) Exclusion Criteria: 1. Alcoholic with Moderate to Severe. 2. BMI \>40 kg/m² 3. Congestive heart disease 4. Positive hepatitis B or hepatitis C, secondary causes of fatty liver (eg. consumption of amiodarone and tamoxifen) and congestive hepatopathy. 5. Severe end organ damage or chronic diseases: renal/hepatic failure, any malignancy, major systemic illness etc.
Where this trial is running
New Delhi, Delhi
- Anoop misra — New Delhi, Delhi, India (Recruiting)
Study contacts
- Principal investigator: Anoop Misra, MD — National Diabetes Obesity and Cholesterol Foundation
- Study coordinator: Anoop Misra, MD
- Email: anoopmisra@gmail.com
- Phone: 01149101222
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.