Comparing dexmedetomidine and remifentanil for pain management after spinal surgery

Comparison of the Effects of Remifentanil and Dexmedetomidine on Postoperative Acute Pain in Patients Who Received Erector Spina Plane Block in Spinal Surgeries

Not applicable Interventional Aydin Adnan Menderes University · NCT06264739

This study tests whether using dexmedetomidine or remifentanil during spinal surgery can help patients manage pain better and use fewer opioids afterward.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment74 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorAydin Adnan Menderes University Academic / other
Locations1 site (Aydın)
Trial IDNCT06264739 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of two different analgesic methods, dexmedetomidine and remifentanil, in patients undergoing erector spinae block for lumbar disc surgery. It is a randomized double-blind study where patients will receive either dexmedetomidine or remifentanil during their surgery, alongside a routine anesthesia protocol. Pain levels will be assessed postoperatively using a Numeric Rating Scale at regular intervals to determine which method provides better pain relief and reduces opioid consumption.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-75 who are scheduled for lumbar disc surgery and have an ASA physical status of 1-3.

Not a fit: Patients who may not benefit from this study include those requiring emergency surgery, those with chronic opioid use, or those with psychiatric disorders.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing spinal surgery, potentially reducing opioid use.

How similar studies have performed: Other studies have shown promising results with similar multimodal analgesia approaches, suggesting potential for success in this trial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Written informed consent;
* 18-75 years old
* ASA Physical Status 1-3;
* Patients planned for lumbar disc surgery

Exclusion Criteria:

* Rejection during registration
* Request for dismissal from employment
* Inability to give informed consent
* Emergency surgery
* Bleeding diathesis
* Chronic use of opioids
* Psychiatric disorders

Where this trial is running

Aydın

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postoperative Acute PainOpioid Consumption
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.