Comparing Dexmedetomidine and Labetalol for Controlled Hypotension in DCR Surgery
The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective Study
This study is testing whether the medications dexmedetomidine or labetalol work better to control blood pressure and reduce bleeding during eye surgery for people with blocked tear ducts.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06346561 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the efficacy of dexmedetomidine and labetalol in achieving controlled hypotension during dacryocystorhinostomy (DCR) surgery for patients with nasolacrimal duct obstruction. Controlled hypotension is crucial in minimizing bleeding during the procedure, and this study seeks to determine which medication provides better hemodynamic stability. The trial will involve patients aged 18 to 60 with specific ASA physical status classifications, and it will assess the outcomes related to bleeding control during surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 60 with ASA physical status I or II.
Not a fit: Patients with significant comorbidities such as hypertension, diabetes, or other severe health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications during DCR surgery for patients with nasolacrimal duct obstruction.
How similar studies have performed: There is limited existing research specifically on controlled hypotension in DCR surgery, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * physical status I or II according to ASA classification, age between ( 18 - 60 years ) Exclusion Criteria: * Patients with physical status other than 1 and 2 according to ASA classification as :Hypertension, Diabetes mellitus, Ischemic heart diseases, Severe anemia, COPD, History of stroke, Impaired liver or renal function, Increase intercranial tension. * Allergy to any of the drug included in this study.
Where this trial is running
Sohag
- Sohag University hospitals — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohammad A Mahmoud, Resident
- Email: mohamedaboelsoad@med.sohag.edu.eg
- Phone: 01090684862
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.