Comparing Dexmedetomidine and Dexamethasone for Pain Relief in Children After Ankle Surgery

Perineural Dexmedetomidine Vs Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery

Phase 4 Interventional Poznan University of Medical Sciences · NCT06304324

This study is testing whether adding Dexmedetomidine or Dexamethasone to pain relief shots can help kids feel less pain and recover faster after ankle surgery.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment90 (estimated)
Ages3 Months to 18 Years
SexAll
SponsorPoznan University of Medical Sciences Academic / other
Locations1 site (Poznań, Wielkopolska)
Trial IDNCT06304324 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of perineural Dexmedetomidine versus Dexamethasone in prolonging the duration of popliteal nerve blocks for pain management following pediatric ankle and foot surgeries. The research aims to determine which adjuvant provides better analgesia and faster recovery for children undergoing these procedures. By comparing two different medications added to local anesthetics, the study seeks to enhance postoperative pain control while ensuring safety in a pediatric population. The trial is conducted at the Poznan University of Medical Sciences in Poland.

Who should consider this trial

Good fit: Ideal candidates for this study are children scheduled for foot or ankle surgery who weigh more than 5 kg.

Not a fit: Patients with infections at the site of the nerve block, coagulation disorders, or those on regular steroid medication may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for children undergoing ankle and foot surgeries.

How similar studies have performed: While there is considerable research on dexamethasone use in adults, this study is novel as it focuses specifically on pediatric patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* children scheduled for foot/ankle surgery
* body weight \> 5kg

Exclusion Criteria:

* infection at the site of the regional blockade
* coagulation disorders
* immunodeficiency
* ASA= or \>4
* steroid medication in regular use

Where this trial is running

Poznań, Wielkopolska

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ankle DiseaseAnkle Injuries and DisordersFoot InjuryFoot Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.