Comparing Dexamethasone and Dexmedetomidine for Pain Relief in Children After Foot Surgery
Dexamethasone Vs. Dexmedetomidine for Popliteal Nerve Block in Pain Management After Pediatric Ankle and Foot Surgery
PHASE4 · Poznan University of Medical Sciences · NCT06233565
This study tests whether adding Dexamethasone or Dexmedetomidine to pain relief shots helps children recover better and feel less pain after foot surgery.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 3 Months to 7 Years |
| Sex | All |
| Sponsor | Poznan University of Medical Sciences (other) |
| Locations | 2 sites (Poznan, Poznań and 1 other locations) |
| Trial ID | NCT06233565 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of perineural Dexamethasone and Dexmedetomidine on the duration of popliteal nerve blocks in children undergoing ankle and foot surgery. It aims to determine which of the two adjuvants provides better pain relief and faster recovery postoperatively. The study involves administering either Dexamethasone or Dexmedetomidine alongside local anesthetics to enhance analgesic effects while minimizing local anesthetic toxicity. The research addresses a significant gap in pediatric pain management, as most existing studies focus on adult populations.
Who should consider this trial
Good fit: Ideal candidates are children aged between 3 months and 7 years scheduled for ankle or foot surgery.
Not a fit: Patients outside the age range of 3 months to 7 years or those with certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for children undergoing foot and ankle surgeries.
How similar studies have performed: While there is considerable research on Dexamethasone and Dexmedetomidine in adults, this approach in pediatric populations is relatively novel and underexplored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all children scheduled for ankle or foot surgery * aged \> 3 months \< 7 years Exclusion Criteria: * age \< 3 months * age \> 7 years * infection at the site of the regional blockade * coagulation disorders * immunodeficiency * ASA= or \>4 * steroid medication in regular use * chronic pain
Where this trial is running
Poznan, Poznań and 1 other locations
- Poznan University of Medical Sciences — Poznan, Poznań, Poland (RECRUITING)
- Department of Spine Diseases and Pediatric Orthopedics, University of Medical Sciences, Poznań, Poland — Poznań, Wielkopolska, Poland (RECRUITING)
Study contacts
- Study coordinator: Malgorzata Domagalska, MD PhD
- Email: m.domagalska@icloud.com
- Phone: +48608762068
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Foot Injuries and Disorders, Ankle Injuries and Disorders