Comparing dairy and plant-based foods in adolescents and older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effects of dairy versus plant-based alternative products on blood sugar regulation and nutrient quality in healthy adolescents and older adults. Participants aged 14-18 and 60-75 will be invited to the Nutrition Intervention Center at the University of Toronto for three visits, including an initial screening and two study visits. Each visit will involve fasting and controlled dietary conditions to accurately assess glycemic response and appetite regulation. The study will last a minimum of two weeks, focusing on the impact of these dietary options on health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 14-18 years old (adolescents) or 60-75 years old (older adults)
* BMI z-score \>+1SD, \<+2SD (adolescents) or BMI 25-30 kg/m2 (older adults)
* Willing to maintain habitual diet, physical activity pattern, and body weight throughout the study.
* Willing to maintain current dietary supplement use throughout the study. On study visit days, subject agrees not to take any supplements until dismissal from the Nutrition Intervention Center.
* Willing to abstain from alcohol consumption for 24hrs prior to all study visits.
* Willing to avoid vigorous physical activity for 24hrs prior to all study visits.
* Willing to refrain from cannabis use throughout the entire duration of the study.
* Willing to refrain from protein supplement use (e.g. protein powder) throughout the entire duration of the study.
* Understands the study procedures, provides informed consent to participate in the study, and authorizes release of relevant protected health information to the study investigator.

Exclusion Criteria:

* Smoking
* Thyroid problems
* Lactose intolerance and/or allergies, intolerances, or sensitivities to study treatments
* Previous history of cardiovascular disease, diabetes, liver or kidney disease, inflammatory bowel disease, celiac disease, short bowel syndrome, malabsorptive syndrome, pancreatitis, gallbladder or biliary disease
* Presence of gastrointestinal disorder or surgeries within the past year.
* Inability to comply with the experimental procedures and follow our safety guidelines
* Regular breakfast skipping (\>3 days a week)
* On a special diet (e.g. ketogenic, Atkins, high protein) or restrained eaters as identified by a score of \>20 on the Eating Attitudes Questionnaire
* Difficulties with eating or swallowing
* Fasting blood glucose \>5.6mmol/L measured at screening
* Uncontrolled hypertension (systolic blood pressure \>120mmHg, diastolic blood pressure \>80mmHg) as defined by the average blood pressure measured at screening
* Weight gain or loss of \>10lbs in previous three months
* Consuming prescription or non-prescription drug, herbal or nutritional supplements known to affect outcome of the study as per investigator's judgement

Where it's running

• Nutrition Intervention Center
  Toronto, Ontario, Canada Recruiting

Study contacts

• Principal investigator: G. Harvey Anderson, PhD — University of Toronto
• Study coordinator: Corrina Zhou, MSc
• Email: corrina.zhou@mail.utoronto.ca
• Phone: 416-946-3802

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.