Comparing daily and weekly iron supplements for infants
Efficacy of Daily and Weekly Iron Supplementation on Anemia Prevalence in Thai Infants Aged 6-12 Months
This study is testing whether giving infants daily or weekly iron supplements is better for reducing anemia and improving their iron levels.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 6 Months to 12 Months |
| Sex | All |
| Sponsor | Mahidol University Academic / other |
| Locations | 1 site (Sam Phran, Nakhon Pathom) |
| Trial ID | NCT06318858 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness of daily versus weekly iron supplementation in infants aged 6-12 months to reduce anemia and improve iron status. Infants will be enrolled at 6 months and randomly assigned to receive either daily or weekly iron supplements for the first 3 months, followed by weekly supplementation for an additional 3 months. Assessments will include hemoglobin levels, serum ferritin levels, and dietary intake at baseline, 9 months, and 12 months. The goal is to determine the best supplementation strategy for improving iron status in infants.
Who should consider this trial
Good fit: Ideal candidates are healthy infants aged 6 months with normal birth weight and hemoglobin levels.
Not a fit: Infants with chronic illnesses or those who have previously taken iron supplements may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into optimal iron supplementation strategies to prevent anemia in infants.
How similar studies have performed: Other studies have shown varying success with iron supplementation in infants, but this specific comparison of daily versus weekly dosing is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Apparently healthy infant, aged 6 months ± 2 weeks * Having a birth weight between 2,500 and 4,000 grams * Being born full term (37 to 41 weeks of age + 6 days) * Having hemoglobin ≥ 10.5 g/dL * Being planned to breastfeed with complementary food and/or complementary foods with formula milk Exclusion Criteria: * Infants with chronic illnesses or thalassemia clinical signs such as anemia, enlarged liver, or spleen (if parental history suggests the child is at risk of developing a thalassemia disease that may not show clinical symptoms) * Previously or currently taking an iron supplement
Where this trial is running
Sam Phran, Nakhon Pathom
- Samphran District Hospital — Sam Phran, Nakhon Pathom, Thailand (Recruiting)
Study contacts
- Principal investigator: Tippawan Pongcharoen, PhD — Mahidol University
- Study coordinator: Tippawan Pongcharoen, PhD
- Email: tippawan.pon@mahidol.ac.th
- Phone: 66813749901
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.