Comparing culturally adapted CBT with standard CBT for anxiety and depression
Feasibility and Acceptability Trial of a Culturally Adapted Manual Versus Standard CBT Manual: A Randomized Control Trial
This study tests if a culturally adapted version of cognitive behavioral therapy can help people with anxiety and depression feel better compared to the standard version.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Pakistan Association of Cognitive Therapists Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Trial ID | NCT06646900 on ClinicalTrials.gov |
What this trial studies
This randomized controlled trial will evaluate the effectiveness, feasibility, and acceptability of a culturally adapted cognitive behavioral therapy (CBT) manual compared to a standard CBT manual. Participants will be randomly assigned to one of the two groups, with the culturally adapted manual incorporating cultural values and norms to enhance therapy relevance. The study aims to determine if these adaptations improve outcomes for individuals experiencing anxiety and depression. The trial will focus on assessing how well each approach works within the target cultural context.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 to 65 years who are experiencing symptoms of anxiety and depression.
Not a fit: Patients with substance use disorders, significant cognitive impairments, or active psychosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective mental health interventions tailored to cultural needs, improving outcomes for patients with anxiety and depression.
How similar studies have performed: Other studies have shown that culturally adapted interventions can improve mental health outcomes, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Individuals aged 18 to 65 years 2. 5 years of education 3. Symptoms of depression and anxiety Exclusion Criteria: 1. Substance use disorder according to DSM-5 criteria as determined by primary care clinician 2. Significant cognitive impairment (for example, profound learning disability or dementia) as determined by primary care clinician 3. Active psychosis as determined by their primary care clinician
Where this trial is running
Lahore, Punjab Province
- Pakistan Association of Cognitive Therapists — Lahore, Punjab Province, Pakistan (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.