Comparing corneal high order aberrations after two types of eye surgery
Comparison of Corneal High Order Aberrations After Stream Light Trans-PRK and Mechanical Photorefractive Keratectomy
This study is testing how two different eye surgeries for nearsightedness affect the shape of the cornea and vision quality before and after the procedures.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 20 Years to 40 Years |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Assiut, Assiut University) |
| Trial ID | NCT06110286 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare corneal high order aberrations before and after two different techniques of photorefractive keratectomy: Stream Light Trans-PRK and Mechanical PRK. It focuses on measuring specific aberrations, including spherical, coma, and trefoil aberrations, using topography assessments from the central corneal zone. The study will evaluate the effectiveness and safety of Stream Light Trans-PRK as a treatment option for low to moderate myopia, contributing to the understanding of how these surgical methods impact corneal shape and vision quality. Data will be collected preoperatively and postoperatively to assess changes in corneal aberrations.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with stable myopia who meet specific corneal and refractive criteria and have not undergone previous ocular surgery.
Not a fit: Patients with uncontrolled systemic diseases, concurrent ocular pathologies, or those who have had previous ocular surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of corneal changes after refractive surgery, leading to improved surgical techniques and patient outcomes.
How similar studies have performed: Previous studies have shown varying success with different refractive surgery techniques, but this specific comparison of Stream Light Trans-PRK and Mechanical PRK is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Stable refraction for 1 year (refraction does not exceed 1D more than the last prescribed glasses). * Discontinuation of soft contact lens wears at least 1 week before examination. * Topography criteria: * Corneal thickness equal or more than 470 um * Symmetrical bow-tie * Back elevation not more than +12 * Normal Belin\\Ambrosio Enhanced ectasia display * Spherical equivalent not more than -6D. Exclusion Criteria: * • Previous ocular surgery * Concurrent ocular pathology; corneal scar, corneal dystrophy * Systemic disease; Uncontrolled diabetes, collagen disease * Post-operative complications; sub-epithelial haze.
Where this trial is running
Assiut, Assiut University
- Assiut university faculty of medicine — Assiut, Assiut University, Egypt (Recruiting)
Study contacts
- Study coordinator: Esraa R Mokhtar, master
- Email: esraarifaat89@gmail.com
- Phone: 01064021834
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.