Comparing color masking effects of two dental treatments for white spot lesions
The Color Masking Potentials of a Bioactive Glass Adhesive and the Resin ICON on the White Spot Lesions. A Comparative Clinical Trial
This study tests which of two dental treatments can better improve the appearance of white spots on teeth that sometimes appear after braces.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 12 Years to 35 Years |
| Sex | All |
| Sponsor | King Abdullah University Hospital Academic / other |
| Locations | 1 site (Irbid) |
| Trial ID | NCT06402500 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of two different treatments for non-cavitated white spot lesions (WSLs) that can occur after orthodontic treatment. A total of 150 teeth will be treated using a split-mouth design, where one quadrant will receive ICON resin infiltration and the other will receive a bioactive glass adhesive. The study aims to evaluate the color masking effects and mineral content changes in WSLs after treatment, using quantitative light-induced fluorescence for assessment. The results will help determine if there are significant differences between the two treatment methods.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with non-cavitated white spot lesions on anterior and premolar teeth who have recently undergone orthodontic treatment.
Not a fit: Patients with cavitated enamel surfaces, developmental enamel defects, or those with conditions such as diabetes or metabolic syndrome may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective treatment option for patients with white spot lesions, improving both aesthetic outcomes and dental health.
How similar studies have performed: Previous studies have shown promising results with resin infiltration techniques for treating white spot lesions, suggesting that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients with teeth and WSL fullfiling the following criteria will be included in the study: 1. Anterior and premolar maxillary and mandibular teeth. 2. Teeth with no previous restorations. 3. post-orthodontic white spot lesions WSL with no adjacent restorations in the same tooth. 4. WSL on Labial surfaces of maxillary or mandibular anterior and premolars teeth. Exclusion Criteria: The following will be excluded from the study, 1. Cavitated enamel surface that requires direct composite restorations. 2. Presence of developmental enamel defects on the proposed teeth. 3. Diabetic patients and patients with metabolic syndrome. 4. Pregnant ladies. 5. Smoker patients.
Where this trial is running
Irbid
- Jordan University of Science and Technology — Irbid, Jordan (Recruiting)
Study contacts
- Principal investigator: Zakereyya SM Albashaireh, PhD — Jordan University of Science and Technology
- Study coordinator: Zakereyya SM Albashaireh, Ph.D
- Email: albashai@just.edu.jo
- Phone: 0096227201000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.