Comparing cold and hot snare techniques for removing small colorectal polyps
Cold Snare Polypectomy Versus Hot Snare Polypectomy for Resection of Small Pedunculated Colorectal Polyps：a Randomized Controlled Trial
NA · Ningbo No. 1 Hospital · NCT06097650
This study is testing whether using cold or hot techniques to remove small colorectal polyps is safer and more effective for patients undergoing this procedure.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 196 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Ningbo No. 1 Hospital (other) |
| Locations | 1 site (Ningbo, Zhejiang) |
| Trial ID | NCT06097650 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness and safety of cold snare polypectomy versus hot snare polypectomy for the removal of small pedunculated colorectal polyps. The study will focus on patients undergoing endoscopic resection at the First Affiliated Hospital of Ningbo University from October 2023 to August 2026. By evaluating the outcomes of both techniques, the trial seeks to provide high-quality clinical evidence that may influence current guidelines for polyp resection strategies. Participants will be randomly assigned to receive either cold or hot snare polypectomy.
Who should consider this trial
Good fit: Ideal candidates for this study are adults undergoing endoscopic resection of small pedunculated polyps who can provide informed consent.
Not a fit: Patients with malignant polyps, severe chronic diseases, or those on anticoagulant therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to safer and more effective methods for removing small colorectal polyps, potentially reducing the risk of complications such as bleeding.
How similar studies have performed: Preliminary studies suggest that cold snare polypectomy may be a safe alternative, but this approach is still under evaluation and may provide new insights compared to existing guidelines.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1. Patients undergoing endoscopic resection of small pedicled polyps in the First Affiliated Hospital of Ningbo University from October 2023 to August 2026; 2. Patients who voluntarily agreed to participate in this study and signed informed consent. Exclusion Criteria: * 1. Persons under 18 years of age 2. Persons unwilling or unable to provide informed consent 3. Treatment or radiotherapy for malignant diseases, severe chronic heart or lung diseases, coronary or cerebrovascular events requiring hospitalization within the last 3 months 4.Malignant polyps have infiltrated the pedicle 5. Abdominal symptoms such as severe abdominal pain, abdominal distension, and nausea 6.Patients with inadequate intestinal preparation 7. Patients with lifelong anticoagulant therapy or severe bleeding diseases, patients who have recently taken anticoagulant drugs or antiplatelet drugs (within 1 week) 8.Pregnant or lactating
Where this trial is running
Ningbo, Zhejiang
- the First Affiliated Hospital of Ningbo University — Ningbo, Zhejiang, China (RECRUITING)
Study contacts
- Study coordinator: Lei Xu
- Email: xulei22@163.com
- Phone: +8613486659126
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pedunculated Colorectal Polyps, Haemorrhage