Comparing ciprofol and propofol for anesthesia in heart surgery
Official title: Ciprofol Versus Propofol for Anesthesia Induction in Cardiac Surgery: A Randomized Double-blind Controlled Clinical Trial
Run by Shanghai East Hospital of Tongji University · NCT06312345 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing a new anesthesia called ciprofol to see if it works better and is safer than the usual anesthesia, propofol, for older patients having heart surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 55 Years to 75 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Shanghai East Hospital of Tongji University Academic / other |
| Locations | 1 site (Shanghai, Shanghai) |
| Trial ID | NCT06312345 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are elective surgery patients aged 55 to 75 with New York Heart Association class II or III cardiac functions.
✕Probably not a fit
Patients with a history of benzodiazepine allergy, significant liver or kidney insufficiency, or other specified exclusions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of ciprofol, a new intravenous anesthetic, compared to propofol for inducing anesthesia in patients undergoing cardiac surgery. The study focuses on patients aged 55 to 75 with specific cardiac function classifications and utilizes a randomized double-blind controlled design to ensure unbiased results. The trial aims to assess the safety and efficacy of ciprofol, particularly its rapid onset and reduced cardiovascular impact, in a surgical setting. By comparing these two anesthetics, the study seeks to provide insights into optimal anesthesia practices for cardiac procedures.
Why it matters
Potential benefit: If successful, this study could lead to improved anesthesia induction methods that enhance patient safety and comfort during cardiac surgeries.
How similar studies have gone: While ciprofol is a novel anesthetic, similar studies comparing anesthetic agents have shown promising results, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Elective surgery patients 2. Aged 55 to 75 3. New York Heart Association class II or III cardiac functions 4. Median sternotomy approach for coronary artery bypass grafting or heart valve replacement procedures Exclusion Criteria: 1. With a history of benzodiazepine allergy 2. Significant liver or kidney insufficiency 3. Coagulation dysfunction 4. Neurological or psychiatric disorders 5. Undergone major surgery within the past three months.
Where it's running
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Shanghai East Hospital of Tongji University
Shanghai, Shanghai, China Recruiting
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.