Comparing cinnamon extract and sodium hypochlorite for treating infected primary teeth
Evaluation Of Antimicrobial Potency Of A Novel Cinnamon Extract Irrigant Versus Sodium Hypochlorite Irrigant Following Pulpectomy Of Primary Teeth . (A Randomized Clinical Trial)
This study is testing whether cinnamon extract can be a safer and effective alternative to sodium hypochlorite for treating infected primary teeth in children aged 4 to 8.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 26 (estimated) |
| Ages | 4 Years to 8 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05860712 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of cinnamon extract compared to sodium hypochlorite as an irrigant during pulpectomy procedures in primary teeth. The focus is on reducing bacterial counts in cases of irreversible pulpitis, where traditional methods may not fully eliminate bacteria due to the complex anatomy of root canals. By using a natural antimicrobial agent like cinnamon, the study aims to address safety concerns associated with synthetic drugs while providing effective treatment for pediatric dental patients. The study involves children aged 4 to 8 who have specific dental conditions and will assess the outcomes of both irrigants in a controlled setting.
Who should consider this trial
Good fit: Ideal candidates are children aged 4 to 8 with carious primary molars exhibiting irreversible pulpitis and who are in good general health.
Not a fit: Patients with severe medical, physical, or mental conditions, or those with un-restorable teeth will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a safer and more effective treatment option for children undergoing dental procedures for infected primary teeth.
How similar studies have performed: While the use of natural antimicrobial agents in dental treatments is gaining interest, this specific comparison of cinnamon extract and sodium hypochlorite is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:
* Children:
1. Aged 4 to 8, in good general health, and medically free.
2. Cooperative patients who will comply to dental treatment .
3. Parents provided with written informed consent.
4. No previous history of antibiotics administration or last dose was taken from at least 2 weeks.
* Teeth:
1. Carious primary molars with irreversible pulpitis.
2. Presence of localized swelling ,sinus and pain on percussion which indicate non vital pulp .
3. Presence of periapical and furcation radiolucency .
4. In periapical radiograph teeth have no more than 1/3 of root resorption.
Exclusion Criteria:
* Children:
1. Children with medical, physical, or mental conditions.
2. Severly Uncooperative children .
* Teeth:
1. Primary molars with any congenital anomalies.
2. Teeth with un-restorable crowns .
3. Root resorbtion more than half of the root.
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Where this trial is running
Cairo
- Cairo university — Cairo, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.