Comparing central and peripheral VA ECMO for heart support
Comparison of Peripheral and Central Intubation on Hemodynamics in Veno-arterial-extracorporeal Membrane Oxygenation (RECOVERY): a National, Multi-center, Prospective, Cohort Study
This study is testing whether using central or peripheral ECMO can help improve blood flow and organ function in patients with severe heart problems.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 136 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT05669183 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to monitor and compare the hemodynamic effects of central versus peripheral veno-arterial extracorporeal membrane oxygenation (VA ECMO) in patients experiencing cardiogenic shock. Participants will be divided into two groups based on the cannulation strategy used, and the study will analyze the efficacy of these strategies on hemodynamics and organ perfusion. The research will provide insights into the potential advantages and disadvantages of each approach, contributing to better clinical decision-making in critical care settings.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are experiencing cardiogenic shock and require VA ECMO support.
Not a fit: Patients with irreversible heart failure, uncontrolled bleeding, or contraindications to anticoagulation therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved outcomes for patients requiring VA ECMO support by identifying the most effective cannulation strategy.
How similar studies have performed: While there have been studies on VA ECMO, this specific comparison of central versus peripheral cannulation strategies is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age≥18 years * Participants with cardiogenic shock * Obtaining informed consent from participants or their affiliated beneficiaries Exclusion Criteria: * Irreversible heart failure * Contraindications to anticoagulation therapy * Uncontrolled bleeding * Irreversible neurological pathology * Participants limited to extracorporeal cardiopulmonary resuscitation
Where this trial is running
Xi'an, Shaanxi
- First Affiliated Hospital of Xi'an Jiaotong University — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Study coordinator: Yang Yan
- Email: yangyan3@xjtu.edu.cn
- Phone: 0086-18991232621
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.