Comparing CCI and POSSUM to predict complications after gynecologic cancer surgery
A Comparison of the Charlson Comorbidity Index (CCI) vs POSSUM Score for Prediction of Perioperative Complications in Patients Undergoing Oncogynecologic Surgery
This project will test whether the Charlson Comorbidity Index (CCI) or the POSSUM score better predicts perioperative complications in adults having elective gynecologic cancer surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Mahidol University Academic / other |
| Locations | 1 site (Bangkok) |
| Trial ID | NCT07287280 on ClinicalTrials.gov |
What this trial studies
This observational, single-center study will retrospectively calculate CCI and POSSUM scores for adults who underwent elective onco-gynecologic surgeries and compare those scores to recorded perioperative complications and mortality. Investigators will extract comorbidity data, physiological measurements, and operative details from clinical charts to derive each risk score. Statistical analyses will compare discrimination and calibration metrics, such as area under the ROC curve, sensitivity, specificity, and calibration plots, for each tool. The goal is to determine which score more reliably identifies patients at higher risk of complications to inform perioperative planning.
Who should consider this trial
Good fit: Adults aged over 18 who underwent elective onco-gynecologic surgery at the study center with complete perioperative records are the intended participants.
Not a fit: Patients who had emergency surgery or whose charts lack key perioperative data (for example, missing anesthetic records) are excluded and would not benefit from the study findings.
Why it matters
Potential benefit: If one score proves more accurate, clinicians could better identify high-risk patients before surgery and target interventions to reduce complications.
How similar studies have performed: Both CCI and POSSUM have shown predictive value in various surgical populations, but direct head-to-head comparisons in onco-gynecologic surgery remain limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * Patient underwent elective onco-gynecologic surgery Exclusion Criteria: * Patient required emergency surgery from any indication * Patient chart that not contained primary outcome data eg. absent of the anesthetic record
Where this trial is running
Bangkok
- Faculty of Medicine Siriraj Hospital, Mahidol University — Bangkok, Thailand (Recruiting)
Study contacts
- Principal investigator: Patchareya Nivatpumin, M.D. — Department of Anesthesiology, Faculty of Medicine Siriraj Hospital
- Study coordinator: Patchareya Nivatpumin, M.D.
- Email: patchareya.niv@mahidol.ac.th
- Phone: +66896662187
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.