Comparing cauterization and fibrin glue for eye surgery in pterygium treatment
Official title: Cauterization Versus fibrin Glue for Conjunctival Autografting in Primary Pterygium Surgery
Run by University of Split, School of Medicine · NCT03321201 · Data updated 2026-11-12
This study tests whether using cauterization or fibrin glue during eye surgery helps prevent pterygium from coming back in patients who need the growth removed.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 164 (estimated) |
| Sponsor | University of Split, School of Medicine Academic / other |
| Locations | 1 site (Split) |
| Status | Recruiting |
| Started | May 8, 2018 |
| Main results expected | May 1, 2025 |
| Study ends | December 31, 2026 |
| Registry record updated | November 2, 2022 |
| Trial ID | NCT03321201 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 with primary nasal pterygia greater than 4 mm that are increasing in size.
✕Probably not a fit
Patients with connective tissue diseases, prior eye surgeries, or those using topical anti-glaucoma medications may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of cauterization versus fibrin glue for conjunctival autografting in patients undergoing primary pterygium surgery. Pterygium is a noncancerous growth that can impair vision and cause discomfort, making surgical removal necessary. The study aims to determine which method reduces the recurrence of pterygium after surgery. Participants will be randomly assigned to receive either cauterization or fibrin glue during their procedure.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced recurrence rates for patients undergoing pterygium surgery.
How similar studies have gone: Other studies have explored various techniques for pterygium surgery, but this specific comparison of cauterization and fibrin glue is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * adults (older than 18 years of age) * both sexes * primary nasal pterygia ˃4 mm, which tends to increase, including patients with reduced visual acuity, chronic inflammation, cosmetic reasons * if the patients had a bilateral pterygium, only one eye will be operated Exclusion criteria: * connective tissue disease * prior eye surgery * chronic use of topical drugs (anti-glaucoma drugs)
Where it's running
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University Hospital Split
Split, Croatia Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Conjunctival transposition surgery for primary pterygium
This surgery tries moving and repositioning your own pterygium tissue during the operation to see if it lowers regrowth and keeps the eye surface healthy in adults with primary pterygium.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.