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Clinical trial Recruiting at 1 site Observational Ages 18 and up

Comparing catheter-based treatments for acute pulmonary embolism

Official title: Cohort Study on Treatment Comes of Catheter-based Therapy in Patients With Acute Pulmonary Embolism in Hong Kong - the HONG KONG PECT Registry

Run by Chinese University of Hong Kong · NCT07029841 · Data updated 2026-11-12

This registry compares outcomes of different catheter-based therapies to see which works best and is safest for people hospitalized with acute pulmonary embolism.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorChinese University of Hong Kong
Academic / other
Locations1 site (Hong Kong, Hong Kong)
StatusRecruiting
StartedJune 1, 2022
Main results expectedDecember 28, 2032
Study endsDecember 30, 2032
Registry record updatedJune 19, 2025
Trial IDNCT07029841 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Patients admitted with acute pulmonary embolism who received any type of catheter-based therapy at participating centers are the ideal candidates for inclusion.

Probably not a fit

Patients managed without catheter-based intervention (for example those treated only with anticoagulation or by surgical embolectomy) may not directly benefit from the study's comparative findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a retrospective cohort analysis of the Hong Kong PECT Registry comparing catheter-directed thrombolysis (including ultrasound-assisted methods) with catheter-based aspiration thrombectomy devices such as Penumbra, FlowTriever, and AlphaVac in patients treated for acute pulmonary embolism. Investigators will extract clinical, procedural, and outcome data from participating hospitals and compare measures including mortality, bleeding, hemodynamic recovery, right ventricular function, and length of stay. Analyses will adjust for baseline risk and PE severity to compare safety and efficacy signals across device classes. The goal is to provide real-world comparative data to inform device selection in routine clinical practice.

Why it matters

Potential benefit: If successful, the results could help clinicians choose the catheter approach that reduces deaths and complications and improves recovery for acute PE patients.

How similar studies have gone: Device-specific trials and registries have reported benefits for some aspiration systems and for ultrasound-assisted catheter-directed thrombolysis, but direct head-to-head comparisons between these approaches are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Patients who is admitted with a diagnosis of acute pulmonary embolism
* Patient who receives any types of catheter-based therapy for acute pulmonary embolism.

Exclusion Criteria:

* nil. This is a all-comer registry.

Where it's running

  • Prince of Wales Hospital
    Hong Kong, Hong Kong, Hong Kong     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.