Comparing catheter-based treatments for acute pulmonary embolism
Cohort Study on Treatment Comes of Catheter-based Therapy in Patients With Acute Pulmonary Embolism in Hong Kong - the HONG KONG PECT Registry
This registry compares outcomes of different catheter-based therapies to see which works best and is safest for people hospitalized with acute pulmonary embolism.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong, Hong Kong) |
| Trial ID | NCT07029841 on ClinicalTrials.gov |
What this trial studies
This is a retrospective cohort analysis of the Hong Kong PECT Registry comparing catheter-directed thrombolysis (including ultrasound-assisted methods) with catheter-based aspiration thrombectomy devices such as Penumbra, FlowTriever, and AlphaVac in patients treated for acute pulmonary embolism. Investigators will extract clinical, procedural, and outcome data from participating hospitals and compare measures including mortality, bleeding, hemodynamic recovery, right ventricular function, and length of stay. Analyses will adjust for baseline risk and PE severity to compare safety and efficacy signals across device classes. The goal is to provide real-world comparative data to inform device selection in routine clinical practice.
Who should consider this trial
Good fit: Patients admitted with acute pulmonary embolism who received any type of catheter-based therapy at participating centers are the ideal candidates for inclusion.
Not a fit: Patients managed without catheter-based intervention (for example those treated only with anticoagulation or by surgical embolectomy) may not directly benefit from the study's comparative findings.
Why it matters
Potential benefit: If successful, the results could help clinicians choose the catheter approach that reduces deaths and complications and improves recovery for acute PE patients.
How similar studies have performed: Device-specific trials and registries have reported benefits for some aspiration systems and for ultrasound-assisted catheter-directed thrombolysis, but direct head-to-head comparisons between these approaches are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who is admitted with a diagnosis of acute pulmonary embolism * Patient who receives any types of catheter-based therapy for acute pulmonary embolism. Exclusion Criteria: * nil. This is a all-comer registry.
Where this trial is running
Hong Kong, Hong Kong
- Prince of Wales Hospital — Hong Kong, Hong Kong, Hong Kong (Recruiting)
Study contacts
- Study coordinator: GuangMing Tan
- Email: gtan@cuhk.edu.hk
- Phone: 852 +55699658
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.