Clinical trial Recruiting at 2 sites Interventional Ages 16 and up

Comparing CAT-guided self-help and CBT-guided self-help for people returning to NHS talking therapy

Official title: Effectiveness and Acceptability of Cognitive Analytic Therapy Guided Self-help (CAT-GSH) for Anxiety and Depression for Returning Patients in NHS Talking Therapies Services

Run by University of Sheffield · NCT06806176 · Data updated 2026-11-12

This project will try CAT-guided self-help and compare it with CBT-guided self-help for people with anxiety or low mood who are returning to NHS Talking Therapies.

Quick facts

Study typeInterventional
Ages16 Years and up
SexAll
Enrollment100 (estimated)
SponsorUniversity of Sheffield
Academic / other
Locations2 sites (Ashton-under-Lyne and 1 other locations)
StatusRecruiting
StartedJuly 30, 2025
Main results expectedDecember 2025
Study endsDecember 2025
Registry record updatedOctober 3, 2025
Trial IDNCT06806176 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with anxiety or depression who previously received CBT-GSH at the same participating NHS Talking Therapies service and are judged suitable for step 2 low-intensity therapy.

Probably not a fit

People who are not fluent in English, who have had high-intensity therapy since their prior CBT-GSH, or who received their prior CBT-GSH at a different service are excluded and may not benefit from the study's findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

A prospective quantitative, quasi-experimental design will compare cognitive analytic therapy-guided self-help (CAT-GSH) with cognitive behavioural therapy-guided self-help (CBT-GSH) in adults returning to NHS Talking Therapies for anxiety or low mood. Eligible participants choose their preferred treatment and receive six one-to-one guided self-help sessions delivered weekly or bi-weekly by PWPs trained in CAT-GSH or providing CBT-GSH. Routine outcome measures already collected by the Talking Therapies services will be collated before, during, and after therapy and analysed to compare effectiveness and acceptability across groups and participant characteristics. The work is being conducted at Tameside and Glossop and Leeds Mental Wellbeing services in collaboration with the University of Sheffield.

Why it matters

Potential benefit: If successful, returning patients could have an effective alternative to CBT-GSH that better meets their needs and improves recovery during low-intensity therapy.

How similar studies have gone: CBT-guided self-help has strong prior evidence for anxiety and depression, while CAT-guided self-help is less established, so this direct comparison is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Previously received CBT-GSH at same participating NHS Talking Therapies service
* Presenting with anxiety or depression
* Deemed suitable for step 2 low-intensity therapy, through assessment by a qualified PWP

Exclusion Criteria:

* Previously received high-intensity therapy since receiving CBT-GSH
* The previous treatment episode was in another NHS Talking Therapies service.
* Not fluent in English

Individuals who are not fluent in English will be excluded from the study due to not having translated CAT-GSH workbooks available and limited funding to translate any workbooks.

Where it's running

  • Tameside and Glossop NHS Talking Therapies Service
    Ashton-under-Lyne, United Kingdom
    Recruiting
  • Leeds Mental Wellbeing Service
    Leeds, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.