Comparing bowel cleansing agents Plenvu and Picoprep before colonoscopy
Official title: A Randomised Controlled Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy
Run by Aalborg University Hospital · NCT05436054 · Data updated 2026-11-12
This study is testing whether Plenvu or Picoprep works better and is easier to handle for people getting ready for a colonoscopy.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Aalborg University Hospital Academic / other |
| Locations | 1 site (Aalborg, North Jutland) |
| Status | Recruiting |
| Started | October 1, 2022 |
| Main results expected | December 1, 2025 |
| Study ends | December 1, 2025 |
| Registry record updated | November 19, 2024 |
| Trial ID | NCT05436054 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who are scheduled for an ambulatory colonoscopy.
✕Probably not a fit
Patients with severe heart or renal failure, pregnant or breastfeeding individuals, and those with specific gastrointestinal conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial aims to compare the efficacy and tolerability of two bowel cleansing agents, Plenvu and Picoprep, prior to colonoscopy. A total of 400 patients referred for colonoscopy at a single center in North Jutland will be randomly assigned to receive either Plenvu or Picoprep. Participants will complete a questionnaire regarding expected side effects and their experience with the bowel cleansing agents. The quality of bowel cleansing will be assessed using a blinded scoring system to ensure unbiased evaluation by the colonoscopist.
Why it matters
Potential benefit: If successful, this study could lead to improved bowel preparation methods, enhancing the effectiveness of colonoscopies and potentially increasing the detection rates of colonic lesions.
How similar studies have gone: Previous studies have shown varying success with different bowel cleansing agents, but this specific comparison of Plenvu and Picoprep is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ambulant colonoscopy * Older than18 Exclusion Criteria: * Younger than 18 * Known with severe heart failure * Known with severe renal failure (eGFR\<30) * Known for colonic stenosis * Pregnant or breastfeeding * Acute colonoscopy * Cancer screening program colonoscopy * Mentally retarded * Redo colonoscopy of patients included in this study and colonoscopy was canceled because of bad bowel preparation. * Patients with Phenylketonuria * Patients with Glucose-6-phosphate-dehydrogenase deficiency * Patients with colon or rectum resection
Where it's running
-
Aalborg University hospital
Aalborg, North Jutland, Denmark Recruiting
Study contacts
- Study coordinator: Hayder Alqaisi
- Email: haidermahmoud1991@gmail.com
- Phone: +4591637005
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.