Comparing bone marrow in patients with follicular lymphoma and healthy controls
Official title: Bone Marrow and Follicular Lymphoma
Run by Rennes University Hospital · NCT06608147 · Data updated 2026-11-12
This study looks at the differences in bone marrow cells between people with follicular lymphoma and healthy individuals to better understand what might cause relapses in the disease.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Rennes University Hospital Academic / other |
| Locations | 1 site (Rennes) |
| Status | Recruiting |
| Started | December 4, 2024 |
| Main results expected | October 1, 2034 |
| Study ends | October 1, 2034 |
| Registry record updated | December 10, 2024 |
| Trial ID | NCT06608147 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults undergoing surgery involving a sternotomy who do not have a history of hematological malignancies.
✕Probably not a fit
Patients with a history of hematological malignancies or those currently receiving immunomodulating treatments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective single-center study aims to investigate the differences in cell composition between the bone marrow of patients diagnosed with follicular lymphoma and that of healthy control subjects. By utilizing samples obtained during surgeries involving sternotomies, the study will establish a bone marrow bank for patients without hematological diseases, which will serve as a control cohort for future clinical trials. The research seeks to enhance understanding of the microenvironment in the bone marrow that may contribute to the relapses seen in follicular lymphoma patients.
Why it matters
Potential benefit: If successful, this study could provide insights into the mechanisms of follicular lymphoma relapses, potentially leading to improved treatment strategies.
How similar studies have gone: While the specific approach of this study is novel, similar studies have shown the importance of understanding the bone marrow microenvironment in hematological conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Major patient * Patient hospitalized in the thoracic, cardiac and vascular surgery department for surgery involving a sternotomy * Patient with free, informed, written consent * Patient covered by a health insurance scheme Exclusion Criteria: * History of haematological malignancy or haemogram disturbance * Immunomodulating treatment: immunosuppressants, corticoids, antineoplastics * Persons covered by articles L. 1121-5 to L. 1121-8 and L. 1122-1-2 of the French Public Health Code (e.g. minors, protected adults, etc.)\].
Where it's running
-
CHU Rennes
Rennes, France Recruiting
Study contacts
- Study coordinator: Juliette Ferrant, MD
- Email: juliette.ferrant@chu-rennes.fr
- Phone: 0299282555
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.