Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparing bone marrow in patients with follicular lymphoma and healthy controls

Official title: Bone Marrow and Follicular Lymphoma

Run by Rennes University Hospital · NCT06608147 · Data updated 2026-11-12

This study looks at the differences in bone marrow cells between people with follicular lymphoma and healthy individuals to better understand what might cause relapses in the disease.

More Follicular Lymphoma trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorRennes University Hospital
Academic / other
Locations1 site (Rennes)
StatusRecruiting
StartedDecember 4, 2024
Main results expectedOctober 1, 2034
Study endsOctober 1, 2034
Registry record updatedDecember 10, 2024
Trial IDNCT06608147 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults undergoing surgery involving a sternotomy who do not have a history of hematological malignancies.

Probably not a fit

Patients with a history of hematological malignancies or those currently receiving immunomodulating treatments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective single-center study aims to investigate the differences in cell composition between the bone marrow of patients diagnosed with follicular lymphoma and that of healthy control subjects. By utilizing samples obtained during surgeries involving sternotomies, the study will establish a bone marrow bank for patients without hematological diseases, which will serve as a control cohort for future clinical trials. The research seeks to enhance understanding of the microenvironment in the bone marrow that may contribute to the relapses seen in follicular lymphoma patients.

Why it matters

Potential benefit: If successful, this study could provide insights into the mechanisms of follicular lymphoma relapses, potentially leading to improved treatment strategies.

How similar studies have gone: While the specific approach of this study is novel, similar studies have shown the importance of understanding the bone marrow microenvironment in hematological conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Major patient
* Patient hospitalized in the thoracic, cardiac and vascular surgery department for surgery involving a sternotomy
* Patient with free, informed, written consent
* Patient covered by a health insurance scheme

Exclusion Criteria:

* History of haematological malignancy or haemogram disturbance
* Immunomodulating treatment: immunosuppressants, corticoids, antineoplastics
* Persons covered by articles L. 1121-5 to L. 1121-8 and L. 1122-1-2 of the French Public Health Code (e.g. minors, protected adults, etc.)\].

Where it's running

  • CHU Rennes
    Rennes, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • Treatment of B-cell malignancies with ALETA-001

    This study is testing a new treatment called ALETA-001 to see if it can help people with relapsed non-Hodgkin lymphoma who didn't respond well to previous therapies.

    Recruiting at 6 sites Phase 1/2 Cancer Research UK · Birmingham and 6 other locations · NCT06045910

  • Treatment of early relapse follicular lymphoma with mosunetuzumab

    This study is testing if a new treatment called mosunetuzumab can help adults with follicular lymphoma who have had a relapse within two years feel better and live longer compared to standard treatments.

    Recruiting at 3 sites Phase 2 Oslo University Hospital · Helsinki and 2 other locations · NCT05849857

  • Long-term Fertility After Lymphoma Treatment in Young Women

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    Recruiting University Hospital, Lille · Lille · NCT05616325

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.