Comparing blood flow restriction training with other training methods for muscle strength and injury prevention

Effects of Additional Blood Flow Restriction and Sham Blood Flow Restriction in Eccentric Exercise on Muscle Strength, Dynamic Stability, and Reduce the Risk of ACL Injury

NA · Udayana University · NCT05951036

This study is testing whether low-load blood flow restriction training can help healthy athletes aged 15-35 build muscle strength and prevent injuries better than other training methods.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages15 Years to 35 Years
SexAll
SponsorUdayana University (other)
Locations1 site (Denpasar, Bali)
Trial IDNCT05951036 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of low-load blood flow restriction training (LL-BFRt) compared to sham LL-BFRt and high-load eccentric training (HL-Et) in healthy athletes aged 15-35. Participants will be randomly assigned to one of three groups and will engage in specific eccentric training exercises designed to assess improvements in muscle strength, dynamic stability, and prevention of ACL injuries. The study will measure outcomes through a series of controlled training sessions and performance assessments.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy individuals aged 15-35 who participate in level 1 sports at least twice a week and have no history of ACL injuries.

Not a fit: Patients with pre-existing health conditions such as hypertension, diabetes, or a history of significant injuries may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance training methods for athletes, leading to improved muscle strength and reduced risk of ACL injuries.

How similar studies have performed: Previous studies on blood flow restriction training have shown promising results, indicating potential benefits in muscle strength and injury prevention, making this approach both relevant and innovative.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being 15-35 years old
* Perform sports level 1 (soccer, basket ball, futsal, combat martial art) at least twice per week.
* Never had an history of ACL injury
* Never had an history of sprain or strain grade III
* Agree to participate until the end of this study period and sign the inform consent

Exclusion Criteria:

* Having hypertension, blood circulation disease, anemia, obesity, diabetes, kidney failure, vena thromboembolic, cancer, and tumor.
* Disabilities or disabled people.

Where this trial is running

Denpasar, Bali

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Healthy Subjects, Sports Level 1, blood flow restriction training, sham blood flow restriction training, BFR, Eccentric training

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.