Comparing Bipedal and Unipedal Exercises for Chronic Ankle Instability
Official title: When to Start Bipedal Exercises in Chronic Ankle Instability?
Run by Istanbul University - Cerrahpasa · NCT06244511 · Data updated 2026-11-12
This study tests whether doing exercises on both feet or just one foot helps people with chronic ankle instability feel stronger and more stable.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Istanbul University - Cerrahpasa Academic / other |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | March 4, 2024 |
| Main results expected | March 1, 2026 |
| Study ends | July 1, 2026 |
| Registry record updated | March 24, 2025 |
| Trial ID | NCT06244511 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals with documented unilateral chronic ankle instability who have experienced a prior ankle sprain at least six months ago.
✕Probably not a fit
Patients with a history of lower extremity surgery or other significant foot-ankle conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of bipedal versus unipedal exercises in patients with chronic ankle instability (CAI). Participants diagnosed with CAI will be divided into two groups, one receiving early bipedal exercises and the other receiving late bipedal exercises. The aim is to assess improvements in proprioception, strength, and overall ankle stability through targeted therapeutic exercises. The study will include voluntary participants who meet specific inclusion criteria and will exclude those with certain pre-existing conditions.
Why it matters
Potential benefit: If successful, this study could lead to more effective rehabilitation strategies for patients suffering from chronic ankle instability.
How similar studies have gone: Other studies have shown promising results with similar therapeutic exercise approaches for ankle instability, suggesting potential for success in this study.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * The documented unilateral ankle instability confirmed through clinical examinations (drawer test, talar tilt test) and MRI in cases requiring differential diagnosis. * A history of an initial ankle sprain occurring at least 6 months ago. * The presence of a recurrent sense of giving way that started at least 6 months ago and has been intermittently persistent. Exclusion Criteria: * Presence of a history of previous surgery in the lower extremity. * Identification of organic and non-organic lesions such as cartilage injuries, periarticular tendon tears, and impingement syndromes. * The existence of a fracture accompanying instability in the foot-ankle. * Presence of congenital deformities in the foot-ankle. * Diagnosis of talus osteochondral lesion. * Diagnosis of ankle arthritis. * Presence of medial ligament lesion. * Existence of peripheral neuropathy. * Presence of additional rheumatological diseases. * Regular moderate-level exercise for at least 3 days a week in the last 6 months.
Where it's running
-
Acibadem Mehmet Ali Aydinlar University
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Ayşenur Erekdağ, MSc — Bezmialem Vakif University
- Study coordinator: Ayşenur Erekdağ, MSc
- Email: aysenurerekdag@gmail.com
- Phone: 05548959013
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.