Comparing biological and mechanical heart valves for valve disease treatment

Long-term Outcomes of Bioprothetic Valve Versus Mechanical Valve

Observational National Taiwan University Hospital · NCT06041308

This study looks at how well biological and mechanical heart valves work for different groups of patients over time after valve replacement surgery.

Quick facts

Study typeObservational
Enrollment30000 (estimated)
AgesN/A to 20 Years
SexAll
SponsorNational Taiwan University Hospital Academic / other
Locations1 site (Taipei)
Trial IDNCT06041308 on ClinicalTrials.gov

What this trial studies

This observational study aims to analyze long-term outcomes of biological versus mechanical heart valves using data from a hospital's integrated medical database and the National Health Insurance database. The research focuses on the effectiveness and performance of these valves in various patient populations, including young individuals, the elderly, and those with specific health conditions. By examining data from patients who underwent valve replacement surgery between 2007 and 2019, the study seeks to provide insights and recommendations for valve selection in different demographics.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with valve diseases who have undergone valve replacement surgery.

Not a fit: Patients under 20 years of age will not benefit from this study as they are excluded from participation.

Why it matters

Potential benefit: If successful, this study could help optimize valve replacement strategies, leading to improved patient outcomes and tailored treatment options.

How similar studies have performed: Other studies have explored similar comparisons between biological and mechanical valves, indicating a growing interest in this area, though specific outcomes may vary.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:This is a retrospective study, and we plan to utilize data from the hospital's integrated medical database and the National Health Insurance database from January 2007 to December 2019. We will identify all patients within the data who were diagnosed with valve diseases and underwent valve replacement surgery.

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Exclusion Criteria:Individuals under 20 years of age.

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Where this trial is running

Taipei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Valve Heart Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.