Comparing Biodentin and Xeno Graft for Preserving Tooth Sockets
Histomorphometric and Radiographic Assessment of Bone After Socket Preservation Using Biodentin Versus Xeno Graft for Socket Preservation of Single Rooted Mandibular Teeth: Randomized Clinical Trial
This study is testing whether Biodentin or Xeno Graft works better for keeping the bone healthy after a single-rooted tooth is removed.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 11 (estimated) |
| Ages | 25 Years to 50 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza) |
| Trial ID | NCT06695208 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of two materials, Biodentin and Xeno Graft, for socket preservation following the extraction of single-rooted mandibular teeth. After tooth extraction, the socket will be filled with either Biodentin or Xeno Graft, and the area will be closed with gel foam and sutures. Cone Beam Computed Tomography (CBCT) scans will be performed at baseline and after six months to measure changes in bone width, followed by a core biopsy and implant placement. The study aims to determine which material provides better outcomes for bone preservation.
Who should consider this trial
Good fit: Ideal candidates are healthy adults aged 25 to 50 with a badly decayed tooth requiring extraction and good oral hygiene.
Not a fit: Patients with poor oral hygiene, smokers, or those with medical conditions that contraindicate surgical procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the outcomes of dental implant procedures by identifying the more effective material for socket preservation.
How similar studies have performed: Previous studies have explored socket preservation techniques, but the specific comparison of Biodentin and Xeno Graft is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients of both sex with badly decayed tooth indicated for extraction * The ages of the patients ranged from 25 to 50 years. * Patients with healthy systemic condition (Medically free) * Adequate inter-arch space for placement of the implant prosthetic part. * Good oral hygiene * Cooperative patients who are willing to commit for 6 months follow up Exclusion Criteria: * Subjected to irradiation in the head and neck area less than 1 year before implantation. * Poor oral hygiene and motivation. * Smokers * Patient with medical condition that contraindicates surgical procedures * Pregnant or nursing. * Substance abuse. * Patients with habits that may jeopardize the implant longevity and affect the results of the study such as alcoholism or parafunctional habits severe bruxism or clenching. * Active infection or severe inflammation in the area intended for implant placement. * Patients on medication that may interfere with healing (corticosteroids, bisphosphonate, Chemo/radio therapy).
Where this trial is running
Giza
- Cairo university — Giza, Egypt (Recruiting)
Study contacts
- Study coordinator: maxim gerges, MSc
- Email: maxim.gerges@dentistry.cu.edu.eg
- Phone: +201011466614
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.