Comparing bio ceramic and epoxy resin sealers for pain after root canal treatment
Official title: Comparison of the Effects of Bio Ceramic and Epoxy Resin-based Sealers on Postoperative Pain After Root Canal Treatment: A Randomized Controlled Trial at Primary Health Care Corporation, Qatar.
Run by Primary Health Care Corporation, Qatar · NCT06543004 · Data updated 2026-11-12
This study is testing whether using bio ceramic sealers or resin-based sealers during root canal treatment causes less pain for patients with a specific dental condition.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Primary Health Care Corporation, Qatar Government |
| Locations | 1 site (Doha) |
| Status | Recruiting |
| Started | October 28, 2024 |
| Main results expected | October 27, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | November 25, 2024 |
| Trial ID | NCT06543004 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with permanent single-rooted teeth diagnosed with asymptomatic apical periodontitis who require root canal treatment.
✕Probably not a fit
Patients with medically compromised conditions, multi-rooted teeth, or those who are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares the effects of bio ceramic sealers and resin-based sealers on postoperative pain in patients undergoing root canal treatment for asymptomatic apical periodontitis. It aims to evaluate the intensity and occurrence of pain and the need for analgesics following the use of these two types of sealers. The study follows a randomized trial design and adheres to CONSORT guidelines to ensure rigorous methodology. Participants will be single-rooted teeth patients diagnosed with the condition and willing to participate.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing root canal treatments.
How similar studies have gone: Retrospective studies have shown varying outcomes related to postoperative pain with different sealers, indicating that this area of research has been explored but may still hold novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Permanent single rooted tooth 1-1 configuration and complete root development. * Requiring root canal treatment. * Diagnosed with Asymptomatic apical periodontitis, teeth asymptomatic, periapical index will exhibit an apical radiolucency. * Willing to Participate. Exclusion Criteria: * Medically compromised patients. * Inability to reach working length, complication during treatment. * Retreatment teeth, multi rooted teeth. * Periodontological compromised teeth. * Uncooperative patients. * Pregnant patients.
Where it's running
-
Primary Health Corporation
Doha, Qatar Recruiting
Study contacts
- Principal investigator: Dareen Azzouz — Primary Health care corporation
- Study coordinator: Dareen Azzouz
- Email: dazzouz@phcc.gov.qa
- Phone: 0097450148511
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Cryotherapy after retreatment of a tooth: does cooling the canal reduce pain and inflammation?
This trial tests whether intracanal cryotherapy with cold saline after endodontic retreatment reduces postoperative pain and inflammatory biomarkers in adults with a single-rooted mandibular premolar and asymptomatic apical periodontitis.
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Postoperative pain and short-term success after two root canal filling methods: cold lateral condensation versus warm vertical obturation
This trial will test whether warm vertical obturation or cold lateral condensation causes less postoperative pain and better short-term healing in adults having root canal treatment for single-rooted necrotic teeth with asymptomatic apical periodontitis.
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Bioceramic versus resin-based root canal sealer and short-term pain
This will test whether a calcium-based bioceramic sealer or a resin-based sealer causes less short-term pain after root canal treatment in adults with asymptomatic apical periodontitis.
-
Activation techniques in antimicrobial photodynamic therapy for retreatment of apical periodontitis
This trial tests whether different methods of agitating methylene blue during antimicrobial photodynamic therapy can improve healing and reduce infection in teeth that prior root canals had treated for asymptomatic apical periodontitis.
-
Conventional and nano-metronidazole irrigation with or without ultrasonic activation for necrotic single-rooted teeth with apical periodontitis
This study tests whether conventional metronidazole or a nano-formulated version, used as root canal irrigants with or without ultrasonic activation, can reduce post-operative pain and endotoxin levels in necrotic single-rooted teeth with apical periodontitis.
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Post-operative Pain and Healing After Root Canal Re-Treatment Using Laser-Activated Irrigation vs Sonic or No Activation
This study tests whether laser-activated irrigation or sonic activation helps reduce post-operative pain and improve healing after re-treating a tooth with persistent apical inflammation, compared to conventional needle irrigation.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.