Clinical trial Recruiting at 1 site Interventional Ages 18 to 60

Comparing bio ceramic and epoxy resin sealers for pain after root canal treatment

Official title: Comparison of the Effects of Bio Ceramic and Epoxy Resin-based Sealers on Postoperative Pain After Root Canal Treatment: A Randomized Controlled Trial at Primary Health Care Corporation, Qatar.

Run by Primary Health Care Corporation, Qatar · NCT06543004 · Data updated 2026-11-12

This study is testing whether using bio ceramic sealers or resin-based sealers during root canal treatment causes less pain for patients with a specific dental condition.

More Apical Periodontitis trials

Quick facts

Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment40 (estimated)
SponsorPrimary Health Care Corporation, Qatar
Government
Locations1 site (Doha)
StatusRecruiting
StartedOctober 28, 2024
Main results expectedOctober 27, 2025
Study endsDecember 31, 2025
Registry record updatedNovember 25, 2024
Trial IDNCT06543004 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with permanent single-rooted teeth diagnosed with asymptomatic apical periodontitis who require root canal treatment.

Probably not a fit

Patients with medically compromised conditions, multi-rooted teeth, or those who are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effects of bio ceramic sealers and resin-based sealers on postoperative pain in patients undergoing root canal treatment for asymptomatic apical periodontitis. It aims to evaluate the intensity and occurrence of pain and the need for analgesics following the use of these two types of sealers. The study follows a randomized trial design and adheres to CONSORT guidelines to ensure rigorous methodology. Participants will be single-rooted teeth patients diagnosed with the condition and willing to participate.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing root canal treatments.

How similar studies have gone: Retrospective studies have shown varying outcomes related to postoperative pain with different sealers, indicating that this area of research has been explored but may still hold novel insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Permanent single rooted tooth 1-1 configuration and complete root development.
* Requiring root canal treatment.
* Diagnosed with Asymptomatic apical periodontitis, teeth asymptomatic, periapical index will exhibit an apical radiolucency.
* Willing to Participate.

Exclusion Criteria:

* Medically compromised patients.
* Inability to reach working length, complication during treatment.
* Retreatment teeth, multi rooted teeth.
* Periodontological compromised teeth.
* Uncooperative patients.
* Pregnant patients.

Where it's running

  • Primary Health Corporation
    Doha, Qatar
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.