Comparing bio ceramic and epoxy resin sealers for pain after root canal treatment

Comparison of the Effects of Bio Ceramic and Epoxy Resin-based Sealers on Postoperative Pain After Root Canal Treatment: A Randomized Controlled Trial at Primary Health Care Corporation, Qatar.

Not applicable Interventional Primary Health Care Corporation, Qatar · NCT06543004

This study is testing whether using bio ceramic sealers or resin-based sealers during root canal treatment causes less pain for patients with a specific dental condition.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorPrimary Health Care Corporation, Qatar Government
Locations1 site (Doha)
Trial IDNCT06543004 on ClinicalTrials.gov

What this trial studies

This study compares the effects of bio ceramic sealers and resin-based sealers on postoperative pain in patients undergoing root canal treatment for asymptomatic apical periodontitis. It aims to evaluate the intensity and occurrence of pain and the need for analgesics following the use of these two types of sealers. The study follows a randomized trial design and adheres to CONSORT guidelines to ensure rigorous methodology. Participants will be single-rooted teeth patients diagnosed with the condition and willing to participate.

Who should consider this trial

Good fit: Ideal candidates are patients with permanent single-rooted teeth diagnosed with asymptomatic apical periodontitis who require root canal treatment.

Not a fit: Patients with medically compromised conditions, multi-rooted teeth, or those who are pregnant may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing root canal treatments.

How similar studies have performed: Retrospective studies have shown varying outcomes related to postoperative pain with different sealers, indicating that this area of research has been explored but may still hold novel insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Permanent single rooted tooth 1-1 configuration and complete root development.
* Requiring root canal treatment.
* Diagnosed with Asymptomatic apical periodontitis, teeth asymptomatic, periapical index will exhibit an apical radiolucency.
* Willing to Participate.

Exclusion Criteria:

* Medically compromised patients.
* Inability to reach working length, complication during treatment.
* Retreatment teeth, multi rooted teeth.
* Periodontological compromised teeth.
* Uncooperative patients.
* Pregnant patients.

Where this trial is running

Doha

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Asymptomatic Apical PeriodontitisBioceramic sealerResin based sealer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.