Comparing automatic and manual ventilation for cardiac arrest patients
Prehospital Automatic Ventilation on Resuscitation Outcomes in Out-of-hospital Cardiac Arrest Patients: a Randomized Controlled Trial
This study tests whether using automatic ventilation is better than manual ventilation for helping patients who have had a cardiac arrest outside of the hospital.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 514 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Hsinchu) |
| Trial ID | NCT06067204 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of automatic ventilation compared to manual ventilation in patients experiencing out-of-hospital cardiac arrest (OHCA). It is a randomized controlled trial where participants will be assigned to either the automatic ventilation group or the manual ventilation group. The study will assess survival rates and overall prognosis for patients, as well as the quality of resuscitation efforts between the two methods. The findings could provide insights into the best practices for emergency medical services in prehospital settings.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who have suffered an out-of-hospital cardiac arrest and received emergency assistance from the Hsinchu County Fire Department.
Not a fit: Patients who are pregnant, have OHCA due to trauma, or have already shown signs of return of spontaneous circulation at the scene will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve survival rates and outcomes for patients experiencing out-of-hospital cardiac arrest.
How similar studies have performed: While there is ongoing research in ventilation strategies for cardiac arrest, this specific comparison of automatic versus manual ventilation in a prehospital setting is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age over 18 years old at the time of occurrence of out-of-hospital cardiac arrest (OHCA). * Attended by the Hsinchu County Fire Department for emergency medical assistance. Exclusion Criteria: * Pregnant women. * OHCA caused by trauma. * Return of spontaneous circulation (ROSC) observed at the scene. * Clearly deceased at the scene (reaching conditions such as decomposition, rigor mortis, severe burns, decapitation, evisceration, or trunk fracture). * Refusal of medical transportation by family members. * No placement of an advanced airway throughout the procedure.
Where this trial is running
Hsinchu
- National Taiwan University Hospital Hsinchu Branch — Hsinchu, Taiwan (Recruiting)
Study contacts
- Study coordinator: Cheng Yi Fan, M.D.
- Email: chengyi.md@gmail.com
- Phone: +886972654382
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.