Comparing atracurium alone versus atracurium with magnesium sulfate for cataract surgery anesthesia
Atracurium Versus Atracurium and Magnesium Sulphate As Adjuvants to Local Anesthetic for Peribulbar Anesthesia in Cataract Surgery
This study is testing whether adding magnesium sulfate to atracurium can improve anesthesia for patients having cataract surgery by making the eye and eyelid numb more effectively.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 180 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | Minia University Academic / other |
| Locations | 1 site (Minya) |
| Trial ID | NCT06600945 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of adding magnesium sulfate to atracurium in a local anesthetic mixture for peribulbar anesthesia during cataract surgery. The goal is to assess the onset and duration of akinesia of the globe and eyelid, which are critical for successful surgery. By using a combination of atracurium and magnesium sulfate, the study aims to enhance the quality of anesthesia while minimizing complications associated with traditional methods. The research focuses on patients undergoing elective cataract surgery and aims to provide insights into improving regional anesthesia techniques.
Who should consider this trial
Good fit: Ideal candidates are patients aged 20-80 years undergoing elective cataract surgery with ASA physical status I or II.
Not a fit: Patients with neuromuscular disorders, certain medication interactions, or specific ocular conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved anesthesia quality and reduced complications during cataract surgery.
How similar studies have performed: Previous studies have indicated that atracurium can enhance peribulbar anesthesia, but the combination with magnesium sulfate is a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing elective cataract surgery (phacoemulsification and intraocular lens implantation). Patients aged 20-80 years. Both sexes. ASA physical status I\&II. Exclusion Criteria: \- Refusal of the patient to participate in the study. Any disorder of neuromuscular system known from history or clinical examination e.g., Guillarian barre syndrome, Myasthenia gravies and Myopathies. Patients are known to have a history of fits. Patients on medication known to interact with neuromuscular blocking drugs as antipyretics (aminoglycosides and tetracyclines), antiarrhythmic (quinidine). Local sepsis. Coagulation abnormalities (INR\>1.4). High myopia with axial length more than 30 mm or less than 21. Mentally retarded patients and failure of proper communication as in deafness. Morbidly obese patients (BMI\>40). Patients with glaucoma (increased IOP\>20mmgh). Patients with history of hypersensitivity to study drugs. Very dense or very soft cataract .
Where this trial is running
Minya
- Dalia yousry mohamed — Minya, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.