Comparing argon plasma coagulation and endoscopic mucosal resection for small gastric adenomas

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Gastric adenomas with low-grade dysplasia are precancerous lesions for which management varies internationally. This interventional trial assigns patients with lesions ≤1 cm to receive either argon plasma coagulation (APC) or endoscopic mucosal resection (EMR) and follows them for completeness of treatment, complication rates, and recurrence. EMR removes the lesion for full pathological assessment but can be more technically demanding, while APC is less invasive and quicker but provides less tissue for pathology. The study aims to provide head-to-head clinical data to guide treatment choices for these small lesions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 20 years or older
* Diagnosed with gastric adenoma with low-grade dysplasia measuring ≤ 1 cm on endoscopy
* Scheduled to undergo endoscopic treatment
* Able and willing to provide written informed consent

Exclusion Criteria:

* Previous treatment for gastric adenoma or gastric cancer
* History of gastrectomy
* Diagnosis of gastric cancer or high-grade dysplasia at the time of enrollment
* Presence of multiple gastric adenomas
* Pregnant, breastfeeding, or possibility of pregnancy
* Uncontrolled chronic illnesses that may interfere with trial participation (e.g., uncontrolled hypertension, uncontrolled diabetes, chronic kidney disease, ascites, heart failure, psychiatric disorders)

Where it's running

• National Cancer Center
  Goyang-si, South Korea Recruiting
• Kangbuk Samsung hospital
  Seoul, South Korea Recruiting
• Samsung Medical Center
  Seoul, South Korea Recruiting

Study contacts

• Principal investigator: Hyuk Lee, MD, PhD — Samsung Medical Center
• Study coordinator: Clinical Research Coordinator
• Email: minjicho630@naver.com
• Phone: 82-2-3410-6853

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.