Comparing anesthesia methods for electroconvulsive therapy in depressed patients
Official title: To Explore the Influence of Different Anesthesia Induction Schemes on the Quality and Clinical Effect of Electroconvulsive Convulsions in Patients With Depression Based on EEG Monitoring
Run by First Affiliated Hospital of Chongqing Medical University · NCT05900245 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study tests how different levels of anesthesia affect the success of electroconvulsive therapy in people with moderate to severe depression.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 24 (estimated) |
| Sponsor | First Affiliated Hospital of Chongqing Medical University Academic / other |
| Locations | 1 site (Chongqing, Chongqing) |
| Trial ID | NCT05900245 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are inpatients aged 18-60 diagnosed with moderate to severe depression according to ICD-11 criteria.
✕Probably not a fit
Patients with bipolar disorder, other mental illnesses, or significant physical health issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effects of different levels of consciousness during anesthesia induction on the quality of electroconvulsive therapy (ECT) in patients with moderate to severe depression. A total of 24 inpatients will be randomly assigned to three groups based on their consciousness index, and their EEG responses will be monitored during the procedure. The study aims to determine how varying anesthesia levels impact seizure duration and overall treatment efficacy. Participants will receive propofol and succinylcholine as part of the anesthesia protocol.
Why it matters
Potential benefit: If successful, this study could enhance the effectiveness of electroconvulsive therapy for patients with depression, potentially improving treatment outcomes and reducing cognitive side effects.
How similar studies have gone: While there have been studies on ECT and anesthesia, this specific approach focusing on consciousness levels during ECT is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * In-patients who meet the diagnostic criteria of moderate and severe depression in the 11th edition of the International Classification of Diseases (ICD-11) * Age 18-60 years old, gender unlimited * Primary school or above education level * Indications for MECT treatment * Normal hearing and vision (including color discrimination) * The patient voluntarily participated in the study and signed the informed consent form, and the guardian also signed the informed consent form. Exclusion Criteria: * History of physical disease, brain organic disease and abuse of alcohol and psychoactive substances * Patients with bipolar disorder * Primary insomnia * Combined with other mental diseases * Combined with obesity, diabetes and other metabolic diseases * Combined with hypertension, cardiovascular disease or cerebrovascular disease * Combined with Alzheimer's disease * Pregnant and lactating women.
Where it's running
-
The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing, China Recruiting
Study contacts
- Study coordinator: Zhao B shu, MM
- Email: bangshuzhao@163.com
- Phone: +8615823079815
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.