Clinical trial Recruiting at 1 site Interventional Ages 20 and up

Comparing an AI avatar video versus a conventional narrated PowerPoint to teach patients about radiotherapy

Official title: Comparison of Patient Understanding and Anxiety According to the Delivery Method of Educational Videos: A Prospective Randomized Study in Radiotherapy Patients

Run by Yonsei University · NCT07550686 · Data updated 2026-11-12

This study will test whether an AI-generated avatar video helps adults scheduled for radiotherapy understand their treatment better and feel less anxious compared with a conventional narrated PowerPoint video.

More Radiotherapy trials

Quick facts

Study typeInterventional
Ages20 Years and up
SexAll
Enrollment136 (estimated)
SponsorYonsei University
Academic / other
Drugs / interventionsradiation
Locations1 site (Yongin-si)
StatusRecruiting
StartedDecember 1, 2025
Main results expectedMay 28, 2027
Study endsNovember 28, 2027
Registry record updatedApril 29, 2026
Trial IDNCT07550686 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20 or older who are scheduled to undergo radiotherapy, have ECOG performance status 0-1, and can watch and comprehend video and audio are ideal candidates.

Probably not a fit

Patients who cannot complete questionnaires because of cognitive impairment or psychiatric disorders, or those unable to follow audio-visual material, are unlikely to benefit from the interventions tested here.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In a randomized, parallel-group design, 136 patients scheduled for radiation therapy at two Yonsei-affiliated institutions will be assigned 1:1 to view either an AI-based avatar educational video or a conventional PowerPoint video with voice narration. Both videos are standardized to about five minutes and contain identical core messages and summary points. Participants complete questionnaires at baseline, immediately after viewing the assigned video, and during the first week of treatment to measure anxiety, knowledge comprehension, and satisfaction. The primary comparison focuses on post-intervention anxiety, with secondary analyses of knowledge, satisfaction, and changes over time.

Why it matters

Potential benefit: If successful, the AI-based video approach could reduce pre-treatment anxiety and improve patients' understanding of radiotherapy, making education more effective and patient-centered.

How similar studies have gone: Traditional educational videos have previously improved patient knowledge and sometimes reduced anxiety, but generative AI avatar delivery is novel with limited prior clinical evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 20 years
* Patients scheduled for radiotherapy
* Ability to watch video and comprehend audio, as assessed by the investigator
* ECOG performance status 0-1

Exclusion Criteria:

* Patients unable to complete questionnaires due to cognitive impairment or psychiatric disorders

Where it's running

  • Yongin Severance Hospital
    Yongin-si, South Korea
    Recruiting

Study contacts

  • Principal investigator: Hwakyung Byun, MD,PhD — ongin Severance Hospital
  • Study coordinator: HwaKyung Byun, MD, PhD
  • Email: hkbyun05@yuhs.ac
  • Phone: +82-31-5189-8166

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.