Comparing an AI avatar video versus a conventional narrated PowerPoint to teach patients about radiotherapy
Comparison of Patient Understanding and Anxiety According to the Delivery Method of Educational Videos: A Prospective Randomized Study in Radiotherapy Patients
This study will test whether an AI-generated avatar video helps adults scheduled for radiotherapy understand their treatment better and feel less anxious compared with a conventional narrated PowerPoint video.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 136 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | Yonsei University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Yongin-si) |
| Trial ID | NCT07550686 on ClinicalTrials.gov |
What this trial studies
In a randomized, parallel-group design, 136 patients scheduled for radiation therapy at two Yonsei-affiliated institutions will be assigned 1:1 to view either an AI-based avatar educational video or a conventional PowerPoint video with voice narration. Both videos are standardized to about five minutes and contain identical core messages and summary points. Participants complete questionnaires at baseline, immediately after viewing the assigned video, and during the first week of treatment to measure anxiety, knowledge comprehension, and satisfaction. The primary comparison focuses on post-intervention anxiety, with secondary analyses of knowledge, satisfaction, and changes over time.
Who should consider this trial
Good fit: Adults aged 20 or older who are scheduled to undergo radiotherapy, have ECOG performance status 0-1, and can watch and comprehend video and audio are ideal candidates.
Not a fit: Patients who cannot complete questionnaires because of cognitive impairment or psychiatric disorders, or those unable to follow audio-visual material, are unlikely to benefit from the interventions tested here.
Why it matters
Potential benefit: If successful, the AI-based video approach could reduce pre-treatment anxiety and improve patients' understanding of radiotherapy, making education more effective and patient-centered.
How similar studies have performed: Traditional educational videos have previously improved patient knowledge and sometimes reduced anxiety, but generative AI avatar delivery is novel with limited prior clinical evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 20 years * Patients scheduled for radiotherapy * Ability to watch video and comprehend audio, as assessed by the investigator * ECOG performance status 0-1 Exclusion Criteria: * Patients unable to complete questionnaires due to cognitive impairment or psychiatric disorders
Where this trial is running
Yongin-si
- Yongin Severance Hospital — Yongin-si, South Korea (Recruiting)
Study contacts
- Principal investigator: Hwakyung Byun, MD,PhD — ongin Severance Hospital
- Study coordinator: HwaKyung Byun, MD, PhD
- Email: hkbyun05@yuhs.ac
- Phone: +82-31-5189-8166
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.