Comparing Allogenic Dentin and Autogenous Dentin for Tooth Extraction Recovery
Evaluation Of Post Extraction Hard Tissue Alteration Following Ridge Preservation in The Esthetic Zone Using Allogeneic Dentin Matrix Versus Autogenous Partially Demineralized Dentine Matrix: A Randomized Controlled Clinical Trial
This study is testing whether using donated dentin or your own dentin after tooth extraction helps keep the bone structure and appearance of your smile better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 32 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo, Cairo, Elmanil, Egypt, 4240101) |
| Trial ID | NCT06477887 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of allogenic dentin matrix versus autogenous partially demineralized dentin matrix in preserving ridge structure after tooth extraction in the aesthetic zone. Patients with unrestorable anterior teeth will undergo periodontal and radiographic examinations to assess their suitability for the study. Following tooth extraction, the two different types of dentin matrices will be applied, and their effects on hard tissue changes will be monitored through various measurements and follow-up visits. The goal is to determine which method better maintains bone structure and aesthetics post-extraction.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 with unrestorable anterior teeth and no more than 50% buccal bone loss.
Not a fit: Patients with systemic conditions affecting healing, poor oral hygiene, or those who smoke may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve outcomes for patients undergoing tooth extractions by enhancing ridge preservation techniques.
How similar studies have performed: While similar approaches have been explored, this specific comparison of allogenic versus autogenous dentin in ridge preservation is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with good health status (ASA-1, ASA-2). * Adult patients over 18 years old. * Patients with non-restorable teeth in the aesthetic zone for periodontal, carious, or traumatic reasons. * Extraction socket with no more than 50% buccal bone loss. * Patients accept a 6-month follow-up period (cooperative patients). * Patients provide informed consent. Exclusion Criteria: * Patients reporting systemic conditions that may compromise healing (e.g., uncontrolled diabetes). * Patients with poor maintenance of oral hygiene. * Pregnancy. * Smokers. * Patients taking any medications that could compromise healing.
Where this trial is running
Cairo, Cairo, Elmanil, Egypt, 4240101
- Cairo University — Cairo, Cairo, Elmanil, Egypt, 4240101, Egypt (Recruiting)
Study contacts
- Study coordinator: Abdullah Matar
- Email: dr.@bood@gmail.com
- Phone: 01203333038
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.