Comparing AI Radiofrequency and Electrical Stimulation for Vulvar Leukoplakia Treatment

A Comparative Study on the Efficacy of AI Temperature-controlled Radiofrequency Technology and Electrical Stimulation in the Treatment of Vulvar Leukoplakia

NA · Zhongnan Hospital · NCT05250466

This study is testing whether a new AI radiofrequency treatment works better than electrical stimulation for helping women with vulvar leukoplakia.

Quick facts

PhaseNA
Study typeInterventional
Enrollment120 (estimated)
Ages18 Years to 60 Years
SexFemale
SponsorZhongnan Hospital (other)
Locations1 site (Wuhan, Hubei)
Trial IDNCT05250466 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness and safety of AI temperature-controlled radiofrequency technology versus electrical stimulation in treating vulvar leukoplakia. It is a multicenter, randomized, open-label trial involving 120 patients, who are divided into two groups for treatment. The study aims to determine which intervention provides better outcomes for patients diagnosed with this condition.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 18 to 60 who have been diagnosed with vulvar leukoplakia.

Not a fit: Patients with severe liver or kidney dysfunction, active infections, cardiovascular diseases, or other significant health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could offer a more effective treatment option for patients suffering from vulvar leukoplakia.

How similar studies have performed: While there is limited information on similar studies, the use of AI technology in medical treatments is an emerging field, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Diagnosed by pathological examination, meeting the diagnostic criteria for leukoplakia;
2. 18 to 60 years old;
3. Agree to sign the informed consent;

Exclusion Criteria:

1. Patients with severe liver and kidney dysfunction;
2. Combined with HIV, syphilis infection, acute vaginitis, cervical cancer;
3. Patients with cardiovascular disease;
4. People with hematological diseases;
5. Patients with hypertension and diabetes;
6. People with mental illness;
7. Pregnant and lactating women.

Where this trial is running

Wuhan, Hubei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Vulvar Lichen Sclerosus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.