Comparing aerobic and resistance exercise in post-menopausal women with type 1 diabetes
Acute Glycemic Effects of Aerobic and Resistance Exercise in Post-menopausal Women With Type 1 Diabetes
NA · University of Alberta · NCT05188027
This study tests whether aerobic or resistance exercise helps post-menopausal women with type 1 diabetes better manage their blood sugar levels.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 45 Years to 75 Years |
| Sex | Female |
| Sponsor | University of Alberta (other) |
| Locations | 2 sites (Edmonton, Alberta and 1 other locations) |
| Trial ID | NCT05188027 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of aerobic versus resistance exercise on blood glucose levels in post-menopausal women with type 1 diabetes. Participants will wear continuous glucose monitors and undergo three testing sessions: a control session with no exercise, a moderate aerobic exercise session, and a moderate weight-lifting session. Blood samples will be collected during and after exercise to assess glucose trends, and various pre-test measures will be taken to evaluate participants' health and fitness levels. The study aims to determine which type of exercise is more beneficial for managing blood glucose levels in this population.
Who should consider this trial
Good fit: Ideal candidates for this study are post-menopausal women diagnosed with type 1 diabetes for at least one year who can perform aerobic and resistance exercises.
Not a fit: Patients with severe peripheral neuropathy, cardiovascular disease, or those with significant comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into optimal exercise regimens for better glucose control in post-menopausal women with type 1 diabetes.
How similar studies have performed: Other studies have shown positive outcomes with exercise interventions in diabetes management, suggesting this approach has potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * type 1 diabetes, diagnosed for at least one year * post-menopause (at least one year since last menstrual period), or have had a hysterectomy and bilateral salpingo oophorectomy * able to perform aerobic and resistance exercise * able to visit the lab in Edmonton, Alberta (University of Alberta) Exclusion Criteria: * HbA1c \> 9.9 % * frequent and unpredictable hypoglycemia * change in insulin management strategy within the last 2 months * blood pressure \> 140 / 95 * severe peripheral neuropathy * history of cardiovascular disease * musculoskeletal injuries interfering with exercise performance * use of medications (other than insulin) that affect glucose metabolism * BMI \> 30 kg/m2 * smoking * moderate to high alcohol intake (\> 2 drinks/day)
Where this trial is running
Edmonton, Alberta and 1 other locations
- Alberta Diabetes Institute — Edmonton, Alberta, Canada (RECRUITING)
- Institut de recherches cliniques de Montréal — Montreal, Quebec, Canada (RECRUITING)
Study contacts
- Study coordinator: Jane E Yardley, PhD
- Email: jane.yardley@ualberta.ca
- Phone: 780-679-1688
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Type 1 Diabetes, Post-menopause, Exercise, Physical activity