Clinical trial Recruiting at 2 sites Interventional Ages 45 to 75 Women only

Comparing aerobic and resistance exercise in post-menopausal women with type 1 diabetes

Official title: Acute Glycemic Effects of Aerobic and Resistance Exercise in Post-menopausal Women With Type 1 Diabetes

Run by University of Alberta · NCT05188027 · Data updated 2026-11-12

This study tests whether aerobic or resistance exercise helps post-menopausal women with type 1 diabetes better manage their blood sugar levels.

Quick facts

Study typeInterventional
Ages45 Years to 75 Years
SexWomen only
Enrollment20 (estimated)
SponsorUniversity of Alberta
Academic / other
Locations2 sites (Edmonton, Alberta and 1 other locations)
StatusRecruiting
StartedNovember 16, 2021
Main results expectedMarch 30, 2027
Study endsMarch 30, 2027
Registry record updatedMarch 16, 2026
Trial IDNCT05188027 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are post-menopausal women diagnosed with type 1 diabetes for at least one year who can perform aerobic and resistance exercises.

Probably not a fit

Patients with severe peripheral neuropathy, cardiovascular disease, or those with significant comorbidities may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of aerobic versus resistance exercise on blood glucose levels in post-menopausal women with type 1 diabetes. Participants will wear continuous glucose monitors and undergo three testing sessions: a control session with no exercise, a moderate aerobic exercise session, and a moderate weight-lifting session. Blood samples will be collected during and after exercise to assess glucose trends, and various pre-test measures will be taken to evaluate participants' health and fitness levels. The study aims to determine which type of exercise is more beneficial for managing blood glucose levels in this population.

Why it matters

Potential benefit: If successful, this study could provide insights into optimal exercise regimens for better glucose control in post-menopausal women with type 1 diabetes.

How similar studies have gone: Other studies have shown positive outcomes with exercise interventions in diabetes management, suggesting this approach has potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* type 1 diabetes, diagnosed for at least one year
* post-menopause (at least one year since last menstrual period), or have had a hysterectomy and bilateral salpingo oophorectomy
* able to perform aerobic and resistance exercise
* able to visit the lab in Edmonton, Alberta (University of Alberta)

Exclusion Criteria:

* HbA1c \> 9.9 %
* frequent and unpredictable hypoglycemia
* change in insulin management strategy within the last 2 months
* blood pressure \> 140 / 95
* severe peripheral neuropathy
* history of cardiovascular disease
* musculoskeletal injuries interfering with exercise performance
* use of medications (other than insulin) that affect glucose metabolism
* BMI \> 30 kg/m2
* smoking
* moderate to high alcohol intake (\> 2 drinks/day)

Where it's running

  • Alberta Diabetes Institute
    Edmonton, Alberta, Canada
    Recruiting
  • Institut de recherches cliniques de Montréal
    Montreal, Quebec, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.