Comparing a self‑cured resin composite with a light‑cured bioactive composite for side cavities in back teeth
Clinical Performance of a Novel Self-cured Resin Composite Compared to a Light-cured Bioactive Resin Composite Restoration in Proximal Cavities of Posterior Teeth: A 2-year Randomized Controlled Clinical Trial
EARLY_PHASE1 · British University In Egypt · NCT07457749
This project will test whether a new self‑cured resin filling works as well as a light‑cured bioactive resin for repairing proximal cavities in adult posterior teeth.
Quick facts
| Phase | EARLY_PHASE1 |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 47 Years |
| Sex | All |
| Sponsor | British University In Egypt (other) |
| Locations | 1 site (Cairo, El Sherouk City) |
| Trial ID | NCT07457749 on ClinicalTrials.gov |
What this trial studies
This single‑center interventional early‑phase study at The British University in Egypt compares clinical performance of a novel self‑cured resin composite against a light‑cured bioactive resin composite in proximal (Class II) cavities of posterior teeth. Adult participants (ages 18–47) with primary caries removal and good or moderate oral hygiene will receive restorations with one of the materials and return for scheduled recall visits for clinical evaluation and maintenance. Teeth with extensive prior restorations, periodontal disease, high caries activity, or other exclusions will be omitted to focus on primary proximal lesions. The trial is designed to see if the self‑cured material can simplify the procedure and maintain acceptable restoration outcomes compared with the light‑cured bioactive option.
Who should consider this trial
Good fit: Adults 18–47 years old with primary proximal caries in posterior teeth, good or moderate oral hygiene, no significant periodontal disease, and willingness to attend follow‑up visits are ideal candidates.
Not a fit: Patients with high caries activity, extensive prior restorations or endodontic treatment, significant periodontal disease, severe bruxism, pregnancy, or caries extending to the cemento‑enamel junction are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, the self‑cured resin could shorten procedure steps and chair time while providing comparable restoration performance.
How similar studies have performed: Related research on bioactive and alternative curing strategies has shown promising results for some materials, but direct comparisons between modern self‑cured and light‑cured bioactive composites remain limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Subjects between the ages of 18-47 years old 2. Primary caries removal 3. Good or moderate oral hygiene 4. Free of periodontal diseases (probing depth and attachment levels within normal limits/ no furcation involvement/ no mobility) 5. Cooperative patients who agree to keep the scheduled recall appointments for data collection and maintenance Exclusion Criteria: 1. Composite or amalgam removal 2. Caries extended to the cemento-enamel junction in Class II caries 3. Grade II or III mobility 4. Considerable periodontal disease without treatment 5. Endodontically treated teeth with extensive loss of tooth tissues 6. Severe wear facets and/or parafunctional activities as clenching or nocturnal bruxism. 7. Subjects who are pregnant during the duration of the study 8. Subjects with high caries activity
Where this trial is running
Cairo, El Sherouk City
- Faculty of Dentistry, The British University in Egypt — Cairo, El Sherouk City, Egypt (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Proximal Cavities of Posterior Teeth, clinical performance, self-cured resin composite, bioactive, proximal cavities