Comparing a self‑cured resin composite with a light‑cured bioactive composite for side cavities in back teeth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single‑center interventional early‑phase study at The British University in Egypt compares clinical performance of a novel self‑cured resin composite against a light‑cured bioactive resin composite in proximal (Class II) cavities of posterior teeth. Adult participants (ages 18–47) with primary caries removal and good or moderate oral hygiene will receive restorations with one of the materials and return for scheduled recall visits for clinical evaluation and maintenance. Teeth with extensive prior restorations, periodontal disease, high caries activity, or other exclusions will be omitted to focus on primary proximal lesions. The trial is designed to see if the self‑cured material can simplify the procedure and maintain acceptable restoration outcomes compared with the light‑cured bioactive option.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Subjects between the ages of 18-47 years old
2. Primary caries removal
3. Good or moderate oral hygiene
4. Free of periodontal diseases (probing depth and attachment levels within normal limits/ no furcation involvement/ no mobility)
5. Cooperative patients who agree to keep the scheduled recall appointments for data collection and maintenance

Exclusion Criteria:

1. Composite or amalgam removal
2. Caries extended to the cemento-enamel junction in Class II caries
3. Grade II or III mobility
4. Considerable periodontal disease without treatment
5. Endodontically treated teeth with extensive loss of tooth tissues
6. Severe wear facets and/or parafunctional activities as clenching or nocturnal bruxism.
7. Subjects who are pregnant during the duration of the study
8. Subjects with high caries activity

Where it's running

• Faculty of Dentistry, The British University in Egypt
  Cairo, El Sherouk City, Egypt Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Salivary IL-8 and Serum IL-6 as Biomarkers to Distinguish Oral Premalignant Disorders in Smokers and Never-Smokers

  This study tests whether salivary IL-8 and blood IL-6 can help tell apart adults with oral premalignant conditions from those with healthy mouths, and whether smoking influences these markers.

  Recruiting British University In Egypt · Cairo · NCT07915570

• Pre-cooling and sweet-tasting solutions to help with dental anesthesia in kids

  This study tests whether pre-cooling and a sweet-tasting substitute given with local anesthesia can reduce pain for children aged 7–11 during dental injections.

  Recruiting British University In Egypt · Cairo, El Sherouk · NCT07835191

• Bone Shell Technique vs Ti-PTFE Membrane for Augmenting the Back of the Jaw

  This study tests whether Khoury’s Bone Shell technique builds more bone than a non-resorbable Ti-PTFE membrane for people with missing teeth in the back of the lower jaw who want implants.

  Recruiting British University In Egypt · Cairo · NCT07669792

• Magnesium membrane versus dual‑zone grafting for immediate implant placement in the aesthetic zone

  This will test whether a magnesium membrane combined with bovine bone gives better bone and gum volume, improved esthetics, and less pain than dual‑zone grafting for adults receiving immediate implants in the upper front teeth.

  Recruiting British University In Egypt · Cairo · NCT07492576

• Connective tissue graft with or without L-PRF to thicken gum tissue around delayed dental implants

  This trial will test whether adding leukocyte platelet-rich fibrin (L-PRF) to a connective tissue graft helps thicken the soft tissue around delayed implants in adults with a thin gingival phenotype.

  Recruiting British University In Egypt · Cairo, Cairo Governorate · NCT07368621

• Restoring two adjacent upper front tooth sockets with vestibular socket therapy and early implants

  This trial will try a minimally invasive vestibular socket therapy plus contour augmentation and early implant placement to restore two adjacent failing upper front teeth.

  Recruiting British University In Egypt · Cairo · NCT07063836

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.