Comparing 7-day and 14-day wound dressings for revision hip and knee surgeries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of two different durations of negative pressure wound therapy (NPWT) dressings in patients undergoing revision hip and knee surgeries. Eligible participants will be randomly assigned to receive either a 7-day or a 14-day NPWT dressing treatment. The study will include a total of 164 patients, with 82 in each surgical cohort, to evaluate which duration is more effective in promoting wound healing. The trial is conducted at a single site, ensuring close monitoring and follow-up of all participants.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects must be over the age of 18 years.
* Participants undergoing aseptic revision hip or aseptic revision knee surgery procedure (a single stage revision procedure).
* Participants must be willing and be able to make all the required study visits to be seen by the research team at the Outpatients department at RJAH.
* Participants must be able to follow instructions.

Exclusion Criteria:

* Revisions for infection, where the nature of the infection has a significant influence on the wound healing, discharge, and length of stay.
* Subjects with a history of poor compliance with medical treatment.
* Subjects with contraindications (as per the PICO Instructions for use) or hypersensitivity to the use of the NPWT PICO dressing product or its components e.g.: silicone adhesives, polyurethane films, acrylic adhesives, polyethylene fabrics and super- absorbent powders (polyacrylates) contained within the dressing.

Where it's running

• Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust
  Oswestry, Shropshire, United Kingdom Recruiting

Study contacts

• Principal investigator: Sudheer L Karlakki — The Robert Jones and Agnes Hunt Orthopaedic Hospital Foundation Trust
• Study coordinator: Julie Steen, BSc. (Hons)
• Email: julie.steen@nhs.net
• Phone: 01691404210

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.