Comparing 3D imaging to CT for assessing pancreatic cancer treatment response

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective multicenter study aims to evaluate the effectiveness of 3D-MSP imaging technology compared to traditional CT scans in assessing the response of patients with borderline or locally advanced pancreatic adenocarcinoma to neoadjuvant chemotherapy. Patients will undergo both imaging techniques prior to surgical exploration, allowing for a direct comparison of their accuracy in predicting surgical outcomes. The study will analyze various accuracy metrics, including sensitivity and specificity, against the gold standard of surgical and histopathological results. By utilizing a within-patient control design, each participant serves as their own control, enhancing the reliability of the findings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Patients with a diagnosis of borderline or locally advanced PAC of the head of the pancreas, as defined by the National Comprehensive Cancer Network (NCCN), who have received neoadjuvant treatment and who undergo surgical exploration with resective intent.

Exclusion Criteria:

* Patients younger than 18 years of age.
* Patients under 18 years of age.
* Disease progression during neoadjuvant treatment.
* No preoperative CT scan.
* Refusal to participate in the study.

Where it's running

• Hospital General de Alicante
  Alicante, Spain Recruiting
• Hospital Universitario de Badajoz
  Badajoz, Spain Recruiting
• Hospital del Mar (Barcelona)
  Barcelona, Spain Recruiting
• Hospital Clínic de Barcelona
  Barcelona, Spain Recruiting
• Hospital de Bellvitge
  Barcelona, Spain Recruiting
• Hospital German Trias y Puyol
  Barcelona, Spain Recruiting

Study contacts

• Study coordinator: Dimitri Dorcaratto
• Email: dorcaratto.dimitri@gmail.com
• Phone: 675441388

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.