Compare three bowel-cleansing methods before colonoscopy: 4-L PEG with bisacodyl and docusate, 2-L PEG with simethicone, and 2-L PEG alone.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial at Tanta University Hospitals enrolls adults aged 18–70 undergoing outpatient colonoscopy and assigns them to one of three bowel-preparation regimens: 4-L split-dose polyethylene glycol with bisacodyl and docusate sodium, 2-L split-dose polyethylene glycol plus oral simethicone, or 2-L split-dose polyethylene glycol alone. Participants will have history-taking, clinical examination, laboratory tests, and a colonoscopy performed 24 hours after starting the preparation. Bowel cleanliness will be rated using the Aronchick bowel preparation scale, and investigators will record adverse events and patient compliance. The trial directly compares safety, tolerability, and cleansing effectiveness across the three regimens.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing colonoscopy as a day-care procedure for various indications (lower GI bleeding, colorectal cancer screening, altered bowel habits, etc.)
* Patients of either sex aged \>18 years and \<70 years.
* Patients willing to give written informed consent.

Exclusion Criteria:

* Presence of Renal failure, cirrhosis, ascites, CCF, bleeding disorders, seizure disorder, gastrointestinal obstruction, or perforation.
* History of serious adverse events to other electrolyte-based colonic lavages.
* Female patients who are pregnant or lactating or considering pregnancy.
* Allergy.

Where it's running

• Tanta University Hospitals
  Tanta, Gharbyea, Egypt Recruiting

Study contacts

• Study coordinator: Rania M Elkafoury, MD
• Email: rania.elkafoury@med.tanta.edu.eg
• Phone: +201004672358

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.