Compare how four pelvic osteotomy techniques change the hip socket shape in children and teens with DDH

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Preoperative hip MRI will be used to create participant-specific 3D pelvis-acetabulum models on which standardized virtual Salter, Dega, San Diego, and Pemberton osteotomies are applied. The team will measure resulting acetabular volume, surface area, coverage distribution, and other predefined 3D morphometric parameters for each virtual technique. Early postoperative MRI (3–8 weeks after surgery) will produce the actual postoperative 3D morphology to compare with the virtual result of the osteotomy actually performed. Validation metrics will include absolute differences, bias, and Bland–Altman limits of agreement, with secondary analyses of reliability, workflow feasibility, and relationships between preoperative markers and prediction error.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 2 to 18 years
2. Developmental dysplasia of the hip or residual acetabular dysplasia
3. Primary Salter, Dega, San Diego, or Pemberton acetabular osteotomy planned at Istanbul University, Istanbul Faculty of Medicine
4. Preoperative hip MRI available within 6 weeks before surgery
5. Early postoperative hip MRI available 3 to 8 weeks after surgery
6. MRI quality adequate for three-dimensional morphometric analysis
7. Unilateral or bilateral cases eligible

Exclusion Criteria:

1. Hip pathology not related to developmental dysplasia of the hip, including Perthes disease, slipped capital femoral epiphysis, neuromuscular dysplasia, or infection/trauma sequelae
2. Previous surgery on the same hip that significantly alters anatomy, including prior pelvic or femoral osteotomy or open reduction, or current metal implant/fusion
3. MRI contraindication or safety issue, including MR-incompatible implant/device, severe claustrophobia, or a medical barrier to sedation/anesthesia
4. MRI not compatible with protocol or inadequate for analysis

Where it's running

• Istanbul University, Istanbul Faculty of Medicine, Department of Orthopedics and Traumatology
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Yavuz Sağlam, M.D. — Istanbul University
• Study coordinator: Yavuz Sağlam, M.D.
• Email: yavuzsaglam84@istanbul.edu.tr
• Phone: +90 536 320 5005

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparing observation and bracing for mild hip dysplasia in infants

  This study tests if watching and monitoring infants with mild hip dysplasia is just as good as using braces to help them, to see if we can avoid unnecessary treatments.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT05869851

• Using ultrasound to assess blood flow during hip surgery for infants with hip dysplasia

  This study is testing if using a special ultrasound during hip surgery can help doctors see blood flow in infants with hip dysplasia to prevent complications and improve surgery results.

  Recruiting Early Phase 1 Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT03107520

• Ocular Changes in People Using Tirzepatide or Semaglutide

  This study checks whether eye structure and blood vessels change in adults with obesity who are taking semaglutide or tirzepatide as part of routine care.

  Recruiting Istanbul University · Istanbul, Istanbul · NCT07924618

• Perfusion Index to Measure Postoperative Pain in Kids After Adenotonsillectomy

  This study tests whether the perfusion index can reliably reflect pain levels in children aged 1–12 after adenotonsillectomy, comparing standard care with an added glossopharyngeal nerve block.

  Recruiting Istanbul University · Istanbul, Istanbul · NCT07915804

• Curcumin topical spray for healing after a first molar extraction

  This study tests whether a curcumin spray applied to the extraction site helps healing and reduces pain compared with chlorhexidine spray or standard care in healthy adults undergoing a first molar extraction.

  Recruiting Istanbul University · Istanbul, Istanbul · NCT07874789

• Neoadjuvant Radiotherapy Before Surgery for Locally Advanced Proximal Rectal Cancer

  This study tests whether giving radiotherapy before surgery reduces cancer return in people with locally advanced proximal rectal cancer.

  Recruiting Istanbul University · Istanbul · NCT07802197

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.