CommunityRx-Kidney Health connects medical, social, and self-care resources for people with chronic kidney disease in rural communities.
CommunityRx-Kidney Health
This project will test whether a tech-driven program that gives personalized community resource referrals plus a clinic navigator can help adults with stages 1–4 chronic kidney disease in rural eastern North Carolina use care better and reduce urgent healthcare visits.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 634 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of North Carolina, Chapel Hill Academic / other |
| Locations | 1 site (Beulaville, North Carolina) |
| Trial ID | NCT07237295 on ClinicalTrials.gov |
What this trial studies
CommunityRx-Kidney Health (CRx-K) is a low-intensity health information technology intervention that combines brief education, a personalized community resource list (HealtheRx), and clinic navigator-led longitudinal support for 12 months. The pragmatic individual-randomized, two-arm, single-blind trial will enroll about 634 adults with CKD stages 1–4 across 35 rural primary care clinics in 16 counties of eastern North Carolina. Participants randomized to CRx-K receive integrated medical, social, and self-care resource referrals and ongoing navigator contact while controls receive usual care. The primary outcome is acute healthcare utilization, with secondary outcomes including self-efficacy for finding resources, knowledge and sharing of integrated care, and measures of CKD management and wellbeing.
Who should consider this trial
Good fit: Adults with stage 1–4 chronic kidney disease who receive care at participating rural primary care clinics in eastern North Carolina and can provide informed consent are the intended participants.
Not a fit: People with end-stage kidney disease or on dialysis, those with limited life expectancy, active cancer treatment, living in skilled nursing facilities, or with significant cognitive impairment are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, CRx-K could reduce emergency visits and hospital stays while helping rural patients better manage CKD and connect to needed social supports like food, housing, and transportation.
How similar studies have performed: Related CommunityRx interventions have shown success connecting patients to social resources in other settings, but this CKD-focused adaptation for rural communities is being specifically tested here.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of chronic kidney disease defined as ≥1 ICD-10 CKD codes (excluding end-stage kidney disease) or CKD biomarkers (estimated glomerular filtration rate ≤ 60 ml/min, albuminuria ≥30 mg/24h) * At least one clinic visit at Goshen Medical Center in 12 months before enrollment Exclusion Criteria: * Limited life expectancy (e.g., advanced cancer, end-stage liver disease, hospice) * Active cancer treatment * Living in a skilled nursing facility * Dementia/other significant cognitive impairment/inability to participate in the informed consent process
Where this trial is running
Beulaville, North Carolina
- Goshen Medical Center — Beulaville, North Carolina, United States (Recruiting)
Study contacts
- Principal investigator: Gaurav J Dave, MBBS, MPH, DrPH — University of North Carolina, Chapel Hill
- Study coordinator: Kristen D Witkemper, MPH
- Email: CRx-K@med.unc.edu
- Phone: 910-939-1879
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.