Community-based rehabilitation for stroke patients using robot-assisted therapy

Rehabilitation Using Community-Based Affordable Robotic Exercise Systems (Rehab CARES)

Not applicable Interventional University of Pennsylvania · NCT05542121

This study is testing if a new robot-assisted therapy can help stroke patients recover better than standard care in their community.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment36 (estimated)
Ages55 Years and up
SexAll
SponsorUniversity of Pennsylvania Academic / other
Locations2 sites (Philadelphia, Pennsylvania and 1 other locations)
Trial IDNCT05542121 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of a robot-assisted therapy system called Rehab CARES for stroke patients in a community-based setting. Patients will undergo a series of clinical assessments before and after receiving either standard care or therapy using the robot system over a four-week period. The study aims to determine the safety, feasibility, and functional outcomes of the robot therapy compared to traditional methods, while also assessing patient motivation and cost-effectiveness. The trial will involve 36 participants who will be randomized into two groups: one receiving standard care and the other receiving robot-assisted therapy.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 55 and older who are more than three months post-stroke and have hemiparesis.

Not a fit: Patients with severe cognitive impairment or those without cerebellum lesions due to stroke may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance rehabilitation outcomes for stroke patients and improve access to quality care in low-resource settings.

How similar studies have performed: Other studies have shown promise with robot-assisted therapies in rehabilitation, indicating potential for success in this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 55 and older (based on who is admitted to the CBR site)
* \>3 months post-stroke
* Stroke diagnosis
* Diagnosis of hemiparesis as a result of stroke (verified by radiology data)
* Motor control score on Upper Extremity Fugl-Meyer scale \> 15 and \< 60;
* Able to understand and speak
* Upper arm manual muscle strength scores \>1
* Pain Scores \< 8 based on NIH Pain Intensity Scale

Exclusion Criteria:

* no cerebellum lesions due to stroke
* severe cognitive function

Where this trial is running

Philadelphia, Pennsylvania and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeHemiplegia
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.