Combining virtual reality and brain stimulation to improve hand function after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of combining virtual reality-based mirror therapy (VRMT) and transcranial direct current stimulation (tDCS) with conventional physical therapy (CPT) to enhance upper limb recovery in stroke patients. Participants will be randomly assigned to one of four groups to assess the impact of these interventions on hand function. The study aims to determine if the combination of VRMT and tDCS provides greater benefits than using either intervention alone. Functional scales will be utilized to evaluate improvements before and after the treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* At least 18 years old.
* Stroke patients with unilateral cerebral infarction or hemorrhage, more than three months following the stroke.
* Adequate cognitive ability to follow instructions (The Arabic version of the Mini-Mental State Examination scores \> 24).
* Modified Ashworth scale score \< 3.
* Fugl-Meyer Assessment (FMA) score of 10-58 indicating moderate-to-severe arm impairment.

Exclusion Criteria:

* visual impairment and field defect or hemi-sensory inattention and unilateral neglect.
* Wernicke's aphasia, or global aphasia, leads to difficulty following instructions.
* Any contraindication to NIBS.
* Other neurological conditions or participation in another study.

Where it's running

• King fahad medical city
  Riyadh, Riyadh Region, Saudi Arabia Recruiting
• King Khalid University Hospital
  Riyadh, Riyadh Region, Saudi Arabia Recruiting

Study contacts

• Principal investigator: Alaa M. Albishi, Doctor of Philosophy — King Saud University
• Study coordinator: Dr. Alaa M. Albishi, Assistant Professor
• Email: aalbeshi@ksu.edu.sa
• Phone: +966555090015

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.