Clinical trial Recruiting at 1 site Phase1; Phase2 Interventional Ages 18 to 60

Combining two techniques to improve recovery after laparoscopic sleeve gastrectomy

Official title: Efficacy of Dexmedetomidine Infusion Combined With Paragastric Neural Block in Enhancing Postoperative Recovery Following Laparoscopic Sleeve Gastrectomy

Run by Alexandria University · NCT06970678 · Data updated 2026-11-12

This study is testing if using a combination of two techniques can help patients recover better and feel less pain after laparoscopic sleeve gastrectomy surgery.

Quick facts

PhasePhase1; Phase2
Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment46 (estimated)
SponsorAlexandria University
Academic / other
Locations1 site (Alexandria)
StatusRecruiting
StartedApril 4, 2025
Main results expectedJune 6, 2025
Study endsJune 18, 2025
Registry record updatedMay 14, 2025
Trial IDNCT06970678 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-60 with a BMI of 35-50 kg/m² and classified as ASA II-III.

Probably not a fit

Patients with chronic pain disorders, those on anticoagulant therapy, or with a history of upper gastrointestinal surgery may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of combining Dexmedetomidine infusion with paragastric autonomic neural block on postoperative recovery in patients undergoing laparoscopic sleeve gastrectomy. The study aims to determine if this combination can enhance recovery quality, reduce opioid consumption, facilitate earlier mobilization, and decrease nausea and vomiting post-surgery. Researchers will evaluate recovery quality using the QoR 40 questionnaire, monitor hemodynamic parameters, and record opioid use and mobilization times. The trial is designed to provide insights into improving postoperative outcomes for patients undergoing this procedure.

Why it matters

Potential benefit: If successful, this approach could lead to faster recovery times and reduced opioid use for patients after laparoscopic sleeve gastrectomy.

How similar studies have gone: While similar approaches have been explored, this specific combination of techniques is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. ASA II-III
2. 18-60 years
3. BMI of 35-50 kg/m²

Exclusion Criteria:

1. Patients with chronic pain disorders
2. Patients using gabapentin, chronic opioid users
3. Patients on anticoagulant therapy
4. Patients with history of upper gastrointestinal system surgery
5. Patients with liver, kidney, cardiovascular diseases
6. Patients with allergy to dexmedetomidine or bupivacaine

Where it's running

  • Alexandria Main University Hospital
    Alexandria, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.