Combining two techniques to improve recovery after laparoscopic sleeve gastrectomy
Official title: Efficacy of Dexmedetomidine Infusion Combined With Paragastric Neural Block in Enhancing Postoperative Recovery Following Laparoscopic Sleeve Gastrectomy
Run by Alexandria University · NCT06970678 · Data updated 2026-11-12
This study is testing if using a combination of two techniques can help patients recover better and feel less pain after laparoscopic sleeve gastrectomy surgery.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 46 (estimated) |
| Sponsor | Alexandria University Academic / other |
| Locations | 1 site (Alexandria) |
| Status | Recruiting |
| Started | April 4, 2025 |
| Main results expected | June 6, 2025 |
| Study ends | June 18, 2025 |
| Registry record updated | May 14, 2025 |
| Trial ID | NCT06970678 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-60 with a BMI of 35-50 kg/m² and classified as ASA II-III.
✕Probably not a fit
Patients with chronic pain disorders, those on anticoagulant therapy, or with a history of upper gastrointestinal surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effects of combining Dexmedetomidine infusion with paragastric autonomic neural block on postoperative recovery in patients undergoing laparoscopic sleeve gastrectomy. The study aims to determine if this combination can enhance recovery quality, reduce opioid consumption, facilitate earlier mobilization, and decrease nausea and vomiting post-surgery. Researchers will evaluate recovery quality using the QoR 40 questionnaire, monitor hemodynamic parameters, and record opioid use and mobilization times. The trial is designed to provide insights into improving postoperative outcomes for patients undergoing this procedure.
Why it matters
Potential benefit: If successful, this approach could lead to faster recovery times and reduced opioid use for patients after laparoscopic sleeve gastrectomy.
How similar studies have gone: While similar approaches have been explored, this specific combination of techniques is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. ASA II-III 2. 18-60 years 3. BMI of 35-50 kg/m² Exclusion Criteria: 1. Patients with chronic pain disorders 2. Patients using gabapentin, chronic opioid users 3. Patients on anticoagulant therapy 4. Patients with history of upper gastrointestinal system surgery 5. Patients with liver, kidney, cardiovascular diseases 6. Patients with allergy to dexmedetomidine or bupivacaine
Where it's running
-
Alexandria Main University Hospital
Alexandria, Egypt Recruiting
Study contacts
- Study coordinator: Mai A El-Sayed, Lecturer of Anesthesia
- Email: m_mohamed165@alexmed.edu.eg
- Phone: 00201287459922
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.