Combining two techniques to improve recovery after laparoscopic sleeve gastrectomy
Efficacy of Dexmedetomidine Infusion Combined With Paragastric Neural Block in Enhancing Postoperative Recovery Following Laparoscopic Sleeve Gastrectomy
This study is testing if using a combination of two techniques can help patients recover better and feel less pain after laparoscopic sleeve gastrectomy surgery.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Enrollment | 46 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Alexandria University Academic / other |
| Locations | 1 site (Alexandria) |
| Trial ID | NCT06970678 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of combining Dexmedetomidine infusion with paragastric autonomic neural block on postoperative recovery in patients undergoing laparoscopic sleeve gastrectomy. The study aims to determine if this combination can enhance recovery quality, reduce opioid consumption, facilitate earlier mobilization, and decrease nausea and vomiting post-surgery. Researchers will evaluate recovery quality using the QoR 40 questionnaire, monitor hemodynamic parameters, and record opioid use and mobilization times. The trial is designed to provide insights into improving postoperative outcomes for patients undergoing this procedure.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-60 with a BMI of 35-50 kg/m² and classified as ASA II-III.
Not a fit: Patients with chronic pain disorders, those on anticoagulant therapy, or with a history of upper gastrointestinal surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to faster recovery times and reduced opioid use for patients after laparoscopic sleeve gastrectomy.
How similar studies have performed: While similar approaches have been explored, this specific combination of techniques is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. ASA II-III 2. 18-60 years 3. BMI of 35-50 kg/m² Exclusion Criteria: 1. Patients with chronic pain disorders 2. Patients using gabapentin, chronic opioid users 3. Patients on anticoagulant therapy 4. Patients with history of upper gastrointestinal system surgery 5. Patients with liver, kidney, cardiovascular diseases 6. Patients with allergy to dexmedetomidine or bupivacaine
Where this trial is running
Alexandria
- Alexandria Main University Hospital — Alexandria, Egypt (Recruiting)
Study contacts
- Study coordinator: Mai A El-Sayed, Lecturer of Anesthesia
- Email: m_mohamed165@alexmed.edu.eg
- Phone: 00201287459922
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.