Clinical trial Recruiting at 1 site Interventional Ages 40 to 65

Combining thoracic spine and shoulder joint mobilization for frozen shoulder

Official title: Additional Effects of Thoracic Spine Mobilization Combined With Glenohumeral Joint Mobilization on Pain, Range of Motion, and Functional Disability in Adhesive Capsulitis

Run by Foundation University Islamabad · NCT07328295 · Data updated 2026-11-12

This trial will see if adding thoracic spine mobilization to shoulder (glenohumeral) mobilization helps people aged 40–65 with adhesive capsulitis reduce pain, improve shoulder motion, and regain function.

Quick facts

Study typeInterventional
Ages40 Years to 65 Years
SexAll
Enrollment34 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Islamabad, Punjab Province)
StatusRecruiting
StartedJanuary 15, 2025
Main results expectedDecember 30, 2025
Study endsJanuary 15, 2026
Registry record updatedJanuary 9, 2026
Trial IDNCT07328295 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 40–65 years old with unilateral or bilateral adhesive capsulitis (stage II or III), at least 3–4 months of shoulder pain, and measurable loss of shoulder ROM are ideal candidates.

Probably not a fit

People with shoulder pain caused by systemic inflammatory disease (e.g., rheumatoid arthritis), recent shoulder fracture/trauma, thoracic outlet syndrome, cervical radiculopathy, spinal myelopathy, infection, or tumors are excluded and unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized controlled trial conducted at a university physical therapy center in Islamabad that compares combined thoracic spine plus glenohumeral joint mobilization versus glenohumeral mobilization alone for adhesive capsulitis. Participants aged 40–65 with stage II or III frozen shoulder and at least 3–4 months of symptoms will be enrolled and randomized to one of the two intervention groups. Outcomes include shoulder pain, range of motion, and functional disability measured over the study period using standardized clinical measures. The protocol applies manual central and unilateral posterior-anterior thoracic mobilizations alongside directed glenohumeral glides to test whether addressing regional interdependence yields superior clinical benefits.

Why it matters

Potential benefit: If successful, this approach could provide greater pain relief, increased shoulder range of motion, and better day-to-day function than glenohumeral mobilization alone.

How similar studies have gone: Biomechanical studies and some clinical reports suggest thoracic mobilization can improve shoulder mechanics, but randomized trials specifically combining thoracic and glenohumeral mobilization for adhesive capsulitis remain limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Both male and female patients with a primary complaint of unilateral or bilateral shoulder pain

  * Pain has persisted for at least 3 to 4 months
  * Decreased shoulder ROM observed, including external shoulder rotation, abduction, internal rotation, and flexion
  * Age range between 40 to 65 years
  * Diagnosed with stage 2nd or 3rd of the disease.

Exclusion Criteria:

* • Patients if they had any shoulder pain resulting from systematic disease such as Rheumatoid Arthritis (morning stiffness \> 1 hour, multiple small joints pain/swelling) Infection, Tumors, and conditions like myelopathy (Hoffman's sign).

  * Recent shoulder joint fracture/ trauma.
  * Thoracic Outlet Syndrome (Roos test).
  * The presence of Cervical radiculopathy (Spurling's test)

Where it's running

  • Foundation University College of Physical Therapy
    Islamabad, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.