Clinical trial Recruiting at 1 site Interventional Ages 50 Months to 65 Months

Combining synergy-based motor therapy and electrical stimulation to improve upper-arm function after stroke

Official title: Effects of Synergy-based Motor Therapy Combined With Neuromuscular Electrical Stimulation in Post Stroke Patients

Run by Riphah International University · NCT07576465 · Data updated 2026-11-12

This study tests whether adding neuromuscular electrical stimulation to synergy-based motor therapy helps people 3–6 months after an ischemic stroke regain use of their affected arm.

Quick facts

Study typeInterventional
Ages50 Months to 65 Months
SexAll
Enrollment40 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Jhang, Punjab Province)
StatusRecruiting
StartedApril 1, 2026
Main results expectedJuly 2026
Study endsJuly 2026
Registry record updatedMay 8, 2026
Trial IDNCT07576465 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 50–65 with a first ischemic stroke 3–6 months earlier, hemiplegia of one upper limb, Modified Ashworth Scale under 2, and Mini‑Mental State Examination above 25.

Probably not a fit

People with recurrent or bilateral strokes, significant cognitive or communication impairment, implanted pacemakers or other contraindications to electrical stimulation, or uncontrolled serious medical conditions are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with a single ischemic stroke 3–6 months earlier and hemiplegic upper limb will receive a rehabilitation program that pairs synergy-based motor therapy (task-focused retraining to reduce abnormal movement patterns) with neuromuscular electrical stimulation to stimulate weak muscles. Treatments are delivered in-person at the District Head Quarter Hospital in Jhang and are compared with conventional therapy approaches. Upper-limb function and daily task performance will be measured before and after the intervention using standard clinical scales and functional tests. The trial excludes people with recurrent or bilateral stroke, significant cognitive impairment, implanted pacemakers, or unstable medical conditions.

Why it matters

Potential benefit: If successful, the combined therapy could speed recovery of arm movement and make daily activities like dressing, eating, and writing easier.

How similar studies have gone: Prior studies show NMES and task-specific motor retraining can each improve post-stroke arm function, and combining them is promising though not yet conclusively proven.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 1\) Age :50 to 65 2) Both male and female 3) Ischemic Stroke onset among 3 to 6 months (sub-acute section) 4) Hemiplegia affected upper limb 5) The score of Modified ash worth scale rating \<2 for upper limb 6) The score of Mini mental state score \>25

Exclusion Criteria:

* 1\) Recurrent stroke or bilateral involvement 2) Cognitive or conversation impairment 3) Presence of pacemaker or contraindications to NMES 4) Uncontrolled comorbid situation (e.g extreme cardiac diseases )

Where it's running

  • District Head Quarter Hospital , Jhang
    Jhang, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.