Combining nerve block and oral dexamethasone to prevent migraine recurrence

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of using peripheral nerve blocks combined with oral dexamethasone to reduce the recurrence of migraine headaches within 72 hours after treatment. Patients who meet specific migraine criteria and show significant pain reduction after nerve blocks will be enrolled. The study aims to determine if this combination therapy can provide better outcomes compared to standard migraine treatments alone. It is the first of its kind to explore this specific combination for migraine management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Meet ICHD-3 Migraine Headache Criteria
* Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2
* Nerve block performed with bupivacaine 0.5%

Exclusion Criteria:

* Head trauma
* Suspicion of secondary headache (i.e. stroke, known tumor, glaucoma)
* Headache in the setting of viral syndrome
* Chronically on steroids
* Known allergy to dexamethasone
* Unable to reach the patient by phone or text for follow-up
* Gestational diabetes or other uncontrolled diabetes
* Known to be immunocompromised

Where it's running

• University Medical Center of El Paso
  El Paso, Texas, United States Recruiting

Study contacts

• Study coordinator: Edward Michelson, MD
• Email: edward.michelson@ttuhsc.edu
• Phone: 915 215 4600

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.